PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 52 件

Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one
分子名称:	3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one, Non-receptor tyrosine-protein kinase TYK2
著者	Skene, R.J.
登録日	2015-12-01
公開日	2016-01-13
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.91 Å)
主引用文献	Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors. J.Med.Chem., 59, 2016

Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with TYK2 activation loop phosphopeptide
分子名称:	Non-receptor tyrosine-protein kinase TYK2 activation loop phosphopeptide, Tyrosine-protein phosphatase non-receptor type 1
著者	Morris, R, Kershaw, N.J, Babon, J.J.
登録日	2022-10-26
公開日	2023-08-16
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023