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PDB: 5 件

5XLN
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BU of 5xln by Molmil
Crystal structure of the TRS_UNE-T and 4EHP complex
分子名称: Eukaryotic translation initiation factor 4E type 2, Threonine--tRNA ligase, cytoplasmic
著者Hwang, J, Nguyen, L.T, Kim, M.H.
登録日2017-05-11
公開日2018-11-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A threonyl-tRNA synthetase-mediated translation initiation machinery.
Nat Commun, 10, 2019
4HWT
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BU of 4hwt by Molmil
Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor
分子名称: N-{[3-(2H-indazol-5-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, cytoplasmic, ...
著者Hilgers, M.T.
登録日2012-11-08
公開日2013-09-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
J.Med.Chem., 56, 2013
4P3N
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BU of 4p3n by Molmil
Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 1
分子名称: (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, Threonine--tRNA ligase, cytoplasmic, ...
著者Fang, P, Yu, X, Chen, K, Chen, X, Guo, M.
登録日2014-03-09
公開日2015-03-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
4TTV
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BU of 4ttv by Molmil
Crystal structure of human ThrRS complexing with a bioengineered macrolide BC194
分子名称: (1R,2R)-2-[(2S,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadec-6-en-2-yl]cyclobutanecarboxylic acid, Threonine--tRNA ligase, cytoplasmic, ...
著者Fang, P, Guo, M.
登録日2014-06-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.
Sci Rep, 5, 2015
1WWT
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BU of 1wwt by Molmil
Solution structure of the TGS domain from human threonyl-tRNA synthetase
分子名称: Threonyl-tRNA synthetase, cytoplasmic
著者Chikayama, E, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-01-18
公開日2005-07-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the TGS domain from human threonyl-tRNA synthetase
To be Published

223166

件を2024-07-31に公開中

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