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PDB: 13 件
7LRU
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BU of 7lru by Molmil
Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer
分子名称: Splicing factor, proline- and glutamine-rich,Isoform 2 of Non-POU domain-containing octamer-binding protein,Isoform Short of Splicing factor, proline- and glutamine-rich
著者Marshall, A.C, Bond, C.S, Mohnen, I, Knott, G.J.
登録日2021-02-17
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of SFPQ-NONO-SFPQ chimeric protein homodimer
To Be Published
7SP0
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BU of 7sp0 by Molmil
Crystal structure of human SFPQ L534I mutant in complex with zinc
分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION
著者Lee, M.
登録日2021-11-01
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons.
Open Biology, 12, 2022
6NCQ
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The dimerization domain of human SFPQ in space group C2221
分子名称: Splicing factor, proline- and glutamine-rich
著者Lee, M.
登録日2018-12-12
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A new crystal structure and small-angle X-ray scattering analysis of the homodimer of human SFPQ.
Acta Crystallogr.,Sect.F, 75, 2019
6OWJ
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BU of 6owj by Molmil
Zn-mediated polymerization of human SFPQ
分子名称: Splicing factor, proline- and glutamine-rich, ZINC ION
著者Lee, M.
登録日2019-05-10
公開日2020-02-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ.
Nucleic Acids Res., 48, 2020
4WII
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BU of 4wii by Molmil
HUMAN SPLICING FACTOR, CONSTRUCT 3
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Splicing factor, ...
著者lee, M, bond, c.s.
登録日2014-09-26
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
5WPA
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BU of 5wpa by Molmil
Structure of human SFPQ/PSPC1 heterodimer
分子名称: Paraspeckle component 1, Splicing factor, proline- and glutamine-rich
著者Lee, M.
登録日2017-08-04
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins.
J. Biol. Chem., 293, 2018
7LRQ
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BU of 7lrq by Molmil
Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region
分子名称: CHLORIDE ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
著者Marshall, A.C, Bond, C.S, Mohnen, I.
登録日2021-02-17
公開日2021-05-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains.
J.Biol.Chem., 298, 2022
7UK1
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BU of 7uk1 by Molmil
Complex Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) with Murine Virus-like 30S Transcript-1 (VS30-1) Reveals Cooperative Binding of RNA
分子名称: MAGNESIUM ION, Splicing factor, proline- and glutamine-rich
著者Lomakin, I.B, Wang, J.
登録日2022-03-31
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
Biochemistry, 61, 2022
6WMZ
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BU of 6wmz by Molmil
Crystal structure of human SFPQ/NONO complex
分子名称: Non-POU domain-containing octamer-binding protein, SULFATE ION, Splicing factor, ...
著者Lee, M, Bond, C.S.
登録日2020-04-22
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure analysis of human SFPQ/NONO complex
To Be Published
7PU5
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Structure of SFPQ-NONO complex
分子名称: MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ...
著者Fribourg, S.
登録日2021-09-28
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.999 Å)
主引用文献Crystal structure of SFPQ-NONO heterodimer.
Biochimie, 198, 2022
4WIK
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HUMAN SPLICING FACTOR, CONSTRUCT 2
分子名称: Splicing factor, proline- and glutamine-rich
著者lee, M, bond, c.s.
登録日2014-09-26
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
4WIJ
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BU of 4wij by Molmil
HUMAN SPLICING FACTOR, CONSTRUCT 1
分子名称: Splicing factor, proline- and glutamine-rich
著者lee, M, bond, c.s.
登録日2014-09-26
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
7UJ1
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BU of 7uj1 by Molmil
Crystal structure of PSF-RNA complex
分子名称: RNA (30-MER), Splicing factor, proline- and glutamine-rich
著者Sachpatzidis, A, Wang, J, Konigsberg, W.H.
登録日2022-03-30
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
Biochemistry, 61, 2022

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件を2024-07-31に公開中

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