6L0A
 
 | | Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2021-12-15 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism
Molecules, 2021
|
|
6L0J
 | | Crystal structure of Dihydroorotase in complex with malate at pH7.5 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | | 主引用文献 | Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism
Molecules, 2021
|
|
6L0G
 | | Crystal structure of dihydroorotase in complex with malate at pH6 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0H
 | | Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.054 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0I
 | | Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
7CA0
 | | Crystal structure of dihydroorotase in complex with 5-fluoroorotic acid from Saccharomyces cerevisiae | | 分子名称: | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode.
Bioinorg Chem Appl, 2021, 2021
|
|
6L0B
 | | Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae | | 分子名称: | 5-FLUOROURACIL, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0F
 | | Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae | | 分子名称: | 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.26 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
6L0K
 | | Crystal structure of dihydroorotase in complex with malate at pH9 from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2019-09-26 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil.
Biochem.Biophys.Res.Commun., 551, 2021
|
|
7CA1
 | | Crystal structure of dihydroorotase in complex with plumbagin from Saccharomyces cerevisiae | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 5-hydroxy-2-methylnaphthalene-1,4-dione, Dihydroorotase, ... | | 著者 | Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. | | 登録日 | 2020-06-08 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis.
Int J Mol Sci, 22, 2021
|
|
