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PDB: 57 件

5V7M
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PCNA mutant L126A/I128A Protein Defective in Gene Silencing
分子名称: MAGNESIUM ION, Proliferating cell nuclear antigen
著者Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
登録日2017-03-20
公開日2018-03-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
8DQX
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Open state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR1
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Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2)
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR3
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Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
1PLQ
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
分子名称: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
著者Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
登録日1995-01-02
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
8DR6
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Closed state of RFC:PCNA bound to a nicked dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR0
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Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR4
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Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD
分子名称: DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
3GPN
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Structure of the non-trimeric form of the E113G PCNA mutant protein
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-03-23
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
3V60
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Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164
分子名称: Proliferating cell nuclear antigen, SULFATE ION, Ubiquitin-like protein SMT3
著者Armstrong, A.A, Mohideen, F, Lima, C.D.
登録日2011-12-18
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
6W9W
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R80A PCNA mutant defective in BIR
分子名称: Proliferating cell nuclear antigen
著者Ripley, B.M, Washington, M.T.
登録日2020-03-23
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
4L6P
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Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair
分子名称: GLYCEROL, Proliferating cell nuclear antigen
著者Washington, T, Boehm, E.
登録日2013-06-12
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
8DR7
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BU of 8dr7 by Molmil
Open state of RFC:PCNA bound to a nicked dsDNA
分子名称: DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR5
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BU of 8dr5 by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
分子名称: DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
2OD8
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BU of 2od8 by Molmil
Structure of a peptide derived from Cdc9 bound to PCNA
分子名称: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen
著者Chapados, B.R, Tainer, J.A.
登録日2006-12-21
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.
Nucleic Acids Res., 35, 2007
3L10
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Structure of split monoubiquitinated PCNA with ubiquitin in position one
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
3PGE
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BU of 3pge by Molmil
Structure of sumoylated PCNA
分子名称: Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen
著者Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T.
登録日2010-11-01
公開日2010-12-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen.
J.Mol.Biol., 406, 2011
3V61
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BU of 3v61 by Molmil
Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164
分子名称: BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ...
著者Armstrong, A.A, Mohideen, F, Lima, C.D.
登録日2011-12-18
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
6D0Q
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BU of 6d0q by Molmil
Structure of a DNA retention-prone PCNA variant
分子名称: Proliferating cell nuclear antigen
著者Kelch, B.A, Gaubitz, C.
登録日2018-04-10
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.80051017 Å)
主引用文献Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
5ZUT
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Crystal Structure of Yeast PCNA in Complex with N24 Peptide
分子名称: N24, Proliferating cell nuclear antigen
著者Cheng, X.Y, Kuang, X.L, Zhou, Y, Xia, X.M, SU, Z.D.
登録日2018-05-08
公開日2018-05-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Crystal Structure of Yeast PCNA in Complex with N24 Peptide
To Be Published
5JNE
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BU of 5jne by Molmil
E2-SUMO-Siz1 E3-SUMO-PCNA complex
分子名称: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ...
著者Lima, C.D, Streich Jr, F.C.
登録日2016-04-29
公開日2016-08-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
1SXJ
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BU of 1sxj by Molmil
Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ...
著者Bowman, G.D, O'Donnell, M, Kuriyan, J.
登録日2004-03-30
公開日2004-06-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex.
Nature, 429, 2004
6D0R
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BU of 6d0r by Molmil
Structure of a DNA retention-prone PCNA variant
分子名称: Proliferating cell nuclear antigen
著者Kelch, B.A, Gaubitz, C.
登録日2018-04-10
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85856962 Å)
主引用文献Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex.
Nucleic Acids Res., 47, 2019
6E49
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Pif1 peptide bound to PCNA trimer
分子名称: ATP-dependent DNA helicase PIF1, Proliferating cell nuclear antigen
著者Buzovetsky, O, Kwon, Y, Pham, N.T, Kim, C, Ira, G, Sung, P, Xiong, Y.
登録日2018-07-17
公開日2018-08-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Role of the Pif1-PCNA Complex in Pol delta-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication.
Cell Rep, 21, 2017

 

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