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PDB: 219 件

7NRT
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Conformation 2 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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Straight filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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Conformation 1 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
5MP1
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Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5
分子名称: Microtubule-associated protein tau, antibody Fab heavy chain, antibody Fab light chain
著者Skrabana, R, Novak, M, Cehlar, O, Kontsekova, E.
登録日2016-12-15
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5
To be published
5N5B
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Structure of Tau(292-319) bound to F-actin
分子名称: Microtubule-associated protein tau
著者Fontela, Y.C, Kadavath, H, Zweckstetter, M.
登録日2017-02-13
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau.
Nat Commun, 8, 2017
5O3L
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Paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5N5A
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Structure of Tau(254-290) bound to F-actin
分子名称: Microtubule-associated protein tau
著者Fontela, Y.C, Kadavath, H, Zweckstetter, M.
登録日2017-02-13
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau.
Nat Commun, 8, 2017
5MO3
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Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 8.5
分子名称: Fab of monoclonal antibody, heavy chain, light chain, ...
著者Skrabana, R, Novak, M.
登録日2016-12-13
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 8.5
To be published
5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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Straight filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5MP5
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Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 6.5
分子名称: Microtubule-associated protein tau, antibody Fab heavy chain, antibody Fab light chain
著者Skrabana, R, Novak, M.
登録日2016-12-15
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 6.5
To be published
7P66
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Globular glial tauopathy type 1 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P67
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Globular glial tauopathy type 2 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P6A
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Limbic-predominant neuronal inclusion body 4R tauopathy type 1a tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P6B
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BU of 7p6b by Molmil
Limbic-predominant neuronal inclusion body 4R tauopathy type 1b tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P6E
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BU of 7p6e by Molmil
Argyrophilic grain disease type 2 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P6D
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BU of 7p6d by Molmil
Argyrophilic grain disease type 1 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P68
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Globular glial tauopathy type 3 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P65
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Progressive supranuclear palsy tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
7P6C
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BU of 7p6c by Molmil
Limbic-predominant neuronal inclusion body 4R tauopathy type 2 tau filament
分子名称: Microtubule-associated protein tau
著者Shi, Y, Zhang, W, Yang, Y, Murzin, A.G, Falcon, B, Kotecha, A, van Beers, M, Tarutani, A, Kametani, F, Garringer, H.J, Vidal, R, Hallinan, G.I, Lashley, T, Saito, Y, Murayama, S, Yoshida, M, Tanaka, H, Kakita, A, Ikeuchi, T, Robinson, A.C, Mann, D.M.A, Kovacs, G.G, Revesz, T, Ghetti, B, Hasegawa, M, Goedert, M, Scheres, S.H.W.
登録日2021-07-15
公開日2021-09-15
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure-based classification of tauopathies.
Nature, 598, 2021
6GX5
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BU of 6gx5 by Molmil
Narrow Pick Filament from Pick's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-06-26
公開日2018-09-12
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
8OTH
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TypeII tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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CTE typeI tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTJ
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PHF tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT9
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CTE typeIII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023

221051

件を2024-06-12に公開中

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