1C6F
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1PQK
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![BU of 1pqk by Molmil](/molmil-images/mine/1pqk) | Repacking of the Core of T4 Lysozyme by Automated Design | 分子名称: | Lysozyme | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | 登録日 | 2003-06-18 | 公開日 | 2003-10-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Repacking the Core of T4 Lysozyme by Automated Design J.Mol.Biol., 332, 2003
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3DMZ
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141L
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143L
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142L
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![BU of 142l by Molmil](/molmil-images/mine/142l) | |
145L
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147L
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190L
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1L96
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![BU of 1l96 by Molmil](/molmil-images/mine/1l96) | STRUCTURE OF A HINGE-BENDING BACTERIOPHAGE T4 LYSOZYME MUTANT, ILE3-> PRO | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME | 著者 | Dixon, M, Shewchuk, L, Matthews, B.W. | 登録日 | 1992-02-11 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro. J.Mol.Biol., 227, 1992
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152L
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198L
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![BU of 198l by Molmil](/molmil-images/mine/198l) | THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | 著者 | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | 登録日 | 1995-11-06 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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1T8A
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![BU of 1t8a by Molmil](/molmil-images/mine/1t8a) | USE OF SEQUENCE DUPLICATION TO ENGINEER A LIGAND-TRIGGERED LONG-DISTANCE MOLECULAR SWITCH IN T4 Lysozyme | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ... | 著者 | Yousef, M.S, Baase, W.A, Matthews, B.W. | 登録日 | 2004-05-11 | 公開日 | 2004-08-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc.Natl.Acad.Sci.USA, 101, 2004
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1LI6
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![BU of 1li6 by Molmil](/molmil-images/mine/1li6) | T4 lysozyme mutant L99A/M102Q bound by 5-methylpyrrole | 分子名称: | 5-METHYLPYRROLE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | 登録日 | 2002-04-17 | 公開日 | 2002-05-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Model Binding Site for Testing Scoring Functions in Molecular Docking J.Mol.Biol., 322, 2002
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1TLA
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![BU of 1tla by Molmil](/molmil-images/mine/1tla) | HYDROPHOBIC CORE REPACKING AND AROMATIC-AROMATIC INTERACTION IN THE THERMOSTABLE MUTANT OF T4 LYSOZYME SER 117 (RIGHT ARROW) PHE | 分子名称: | CHLORIDE ION, PHOSPHATE ION, T4 LYSOZYME | 著者 | Anderson, D.E, Hurley, J.H, Nicholson, H, Baase, W.A, Matthews, B.W. | 登録日 | 1993-03-22 | 公開日 | 1993-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe. Protein Sci., 2, 1993
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1OVJ
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![BU of 1ovj by Molmil](/molmil-images/mine/1ovj) | T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 3-Fluoro-2-Methyl_Aniline | 分子名称: | 3-FLUORO-2-METHYL-ANILINE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Wei, B.Q, Baase, W.A, Weaver, L.H, Matthews, B.W, Shoichet, B.K. | 登録日 | 2003-03-26 | 公開日 | 2004-04-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Testing a Flexible-receptor Docking Algorithm in a Model Binding Site J.Mol.Biol., 337, 2004
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2HUK
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4YX7
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5V83
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![BU of 5v83 by Molmil](/molmil-images/mine/5v83) | Structure of DCN1 bound to NAcM-HIT | 分子名称: | Lysozyme,DCN1-like protein 1 chimera, N-(1-benzylpiperidin-4-yl)-N'-[3-(trifluoromethyl)phenyl]urea | 著者 | Guy, R.K, Schulman, B.A, Scott, D.C, Hammill, J.T. | 登録日 | 2017-03-21 | 公開日 | 2017-05-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat. Chem. Biol., 13, 2017
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1CX6
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2OEA
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![BU of 2oea by Molmil](/molmil-images/mine/2oea) | High-pressure structure of pseudo-WT T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
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1T6H
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![BU of 1t6h by Molmil](/molmil-images/mine/1t6h) | Crystal Structure T4 Lysozyme incorporating an unnatural amino acid p-iodo-L-phenylalanine at position 153 | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Spraggon, G, Xie, J, Wang, L, Wu, N, Brock, A, Schultz, P.G. | 登録日 | 2004-05-06 | 公開日 | 2004-10-26 | 最終更新日 | 2018-02-14 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination. Nat.Biotechnol., 22, 2004
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2OE9
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![BU of 2oe9 by Molmil](/molmil-images/mine/2oe9) | High-pressure structure of pseudo-WT T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
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1L0K
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![BU of 1l0k by Molmil](/molmil-images/mine/1l0k) | METHIONINE CORE MUTANT OF T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME | 著者 | Gassner, N.C, Baase, W.A, Mooers, B.H, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.W. | 登録日 | 2002-02-11 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability BIOPHYS.CHEM., 100, 2003
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3HT9
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![BU of 3ht9 by Molmil](/molmil-images/mine/3ht9) | 2-methoxyphenol in complex with T4 lysozyme L99A/M102Q | 分子名称: | BETA-MERCAPTOETHANOL, Guaiacol, Lysozyme, ... | 著者 | Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. | 登録日 | 2009-06-11 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
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