5LG3
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with chlorpromazine | 分子名称: | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Gamma-aminobutyric-acid receptor subunit beta-1 | 著者 | Nys, M, Wijckmans, E, Farinha, A, Brams, M, Spurny, R, Ulens, C. | 登録日 | 2016-07-05 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.567 Å) | 主引用文献 | Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine. Proc.Natl.Acad.Sci.USA, 113, 2016
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8F32
| ELIC with Propylamine in SMA nanodiscs with 2:1:1 POPC:POPE:POPG | 分子名称: | 3-AMINOPROPANE, Erwinia chrysanthemi ligand-gated ion channel | 著者 | Dalal, V, Arcario, M.J, Petroff II, J.T, Deitzen, N.M, Tan, B.K, Brannigan, G, Cheng, W.W.L. | 登録日 | 2022-11-09 | 公開日 | 2023-11-15 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel. Nat Commun, 15, 2024
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3UQ7
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240S F247L (L9S F16L) in presence of 10 mM cysteamine | 分子名称: | Gamma-aminobutyric-acid receptor subunit beta-1 | 著者 | Gonzalez-Gutierrez, G, Lukk, T, Agarwal, V, Papke, D, Nair, S.K, Grosman, C. | 登録日 | 2011-11-19 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc.Natl.Acad.Sci.USA, 109, 2012
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6V0B
| Unliganded ELIC in POPC-only nanodiscs. | 分子名称: | Gamma-aminobutyric-acid receptor subunit beta-1 | 著者 | Grosman, C, Kumar, P. | 登録日 | 2019-11-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc.Natl.Acad.Sci.USA, 117, 2020
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3UQ5
| X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240A F247L (L9A F16L) in the presence of 10 mM cysteamine | 分子名称: | Gamma-aminobutyric-acid receptor subunit beta-1, SODIUM ION | 著者 | Gonzalez-Gutierrez, G, Lukk, T, Agarwal, V, Papke, D, Nair, S.K, Grosman, C. | 登録日 | 2011-11-19 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc.Natl.Acad.Sci.USA, 109, 2012
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5HEW
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