3S8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s8p by Molmil](/molmil-images/mine/3s8p) | Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine | 分子名称: | Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ZINC ION | 著者 | Lam, R, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2011-05-30 | 公開日 | 2011-07-06 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Febs Lett., 587, 2013
|
|
5CPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5cpr by Molmil](/molmil-images/mine/5cpr) | The novel SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity | 分子名称: | 6,7-dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthalazin-1-amine, Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ... | 著者 | Jakob, C.G, Upadhyay, A.K, Sun, C. | 登録日 | 2015-07-21 | 公開日 | 2017-01-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Nat. Chem. Biol., 13, 2017
|
|
5WBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wbv by Molmil](/molmil-images/mine/5wbv) | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor | 分子名称: | 2-chloro-5-(4-methyl-6-oxo-3-phenylpyrano[2,3-c]pyrazol-1(6H)-yl)benzoic acid, Histone-lysine N-methyltransferase KMT5B, S-ADENOSYLMETHIONINE, ... | 著者 | Halabelian, L, Tempel, W, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2017-06-29 | 公開日 | 2017-07-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor To be published
|
|
8T9F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t9f by Molmil](/molmil-images/mine/8t9f) | |
7YRD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yrd by Molmil](/molmil-images/mine/7yrd) | histone methyltransferase | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | 著者 | Li, H, Wang, W.Y. | 登録日 | 2022-08-09 | 公開日 | 2023-08-16 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
|
|
8T9H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8t9h by Molmil](/molmil-images/mine/8t9h) | |
8JHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jhg by Molmil](/molmil-images/mine/8jhg) | Native SUV420H1 bound to 167-bp nucleosome | 分子名称: | DNA (160-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Lin, F, Li, W. | 登録日 | 2023-05-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | 主引用文献 | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase. Cell Discov, 9, 2023
|
|
8JHF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jhf by Molmil](/molmil-images/mine/8jhf) | Native SUV420H1 bound to 167-bp nucleosome | 分子名称: | DNA (160-MER), Histone H2A.Z, Histone H2B type 1-K, ... | 著者 | Lin, F, Li, W. | 登録日 | 2023-05-23 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase. Cell Discov, 9, 2023
|
|
7YRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yrg by Molmil](/molmil-images/mine/7yrg) | histone methyltransferase | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | 著者 | Li, H, Wang, W.Y. | 登録日 | 2022-08-09 | 公開日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
|
|