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PDB: 49 件
3WE6
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Crystal structure of anti-Prostaglandin E2 Fab fragment
分子名称: ISOPROPYL ALCOHOL, mAb Fab H fragment, mAb Fab L fragment
著者Sugahara, M, Ago, H, Saino, H, Miyano, M.
登録日2013-07-01
公開日2014-07-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of anti-Prostaglandin E2 Fab fragment with Prostaglandin E2
To be Published
2R0Z
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PFA1 FAB complexed with GripI peptide fragment
分子名称: GLYCEROL, GripI peptide fragment, IgG2a Fab fragment heavy chain, ...
著者Gardberg, A.S, Dealwis, C.
登録日2007-08-21
公開日2007-10-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
2DTM
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Thermodynamic and structural analyses of hydrolytic mechanism by catalytic antibodies
分子名称: IMMUNOGLOBULIN 6D9
著者Oda, M, Ito, N, Tsumuraya, T, Suzuki, K, Fujii, I.
登録日2006-07-13
公開日2007-05-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis
J.Mol.Biol., 369, 2007
2IQ9
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PFA2 FAB fragment, triclinic apo form
分子名称: ACETAMIDE, IgG2a Fab fragment PFA2 Kappa light chain, IgG2a Fab fragment PFA2 heavy chain
著者Gardberg, A.S, Dealwis, C.
登録日2006-10-13
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
1M7D
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Crystal structure of a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide complexed with a trisaccharide
分子名称: alpha-L-rhamnopyranose-(1-3)-alpha-L-Olivopyranose-(1-3)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-19
公開日2003-07-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
4OCX
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BU of 4ocx by Molmil
Fab complex with methotrexate
分子名称: Fab ADD056 Heavy Chain, Fab ADD056 Light Chain, N-(4-{[(2,4-DIAMINOPTERIDIN-1-IUM-6-YL)METHYL](METHYL)AMINO}BENZOYL)-L-GLUTAMIC ACID
著者Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S.
登録日2014-01-09
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Water channel in the binding site of a high affinity anti-methotrexate antibody.
Biochemistry, 53, 2014
4HDI
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BU of 4hdi by Molmil
Crystal Structure of 3E5 IgG3 FAB from mus musculus
分子名称: Ig heavy chain V region RF, Ig gamma-3 chain C region, Kappa light chain variable region, ...
著者Janda, A, Eryilmaz, E, Kim, J, Cordero, R.J.B, Cowburn, D, Casadevall, A.
登録日2012-10-02
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.449 Å)
主引用文献Global structures of IgG isotypes expressing identical variable regions.
Mol.Immunol., 56, 2013
1M7I
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CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE
分子名称: alpha-L-rhamnopyranose-(1-2)-alpha-L-rhamnopyranose-(1-3)-alpha-L-rhamnopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-methyl 6-deoxy-alpha-L-rhamnopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-19
公開日2003-07-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics
Biochemistry, 41, 2002
1MNU
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UNLIGANDED BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (HEAVY CHAIN)), PROTEIN (IGG2A-KAPPA ANTIBODY MN12H2 (LIGHT CHAIN))
著者Van Den Elsen, J, Vandeputte-Rutten, L, Kroon, J, Gros, P.
登録日1999-04-30
公開日1999-05-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bactericidal antibody recognition of meningococcal PorA by induced fit. Comparison of liganded and unliganded Fab structures.
J.Biol.Chem., 274, 1999
2R0W
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PFA2 FAB complexed with Abeta1-8
分子名称: Amyloid beta peptide fragment, IgG2a Fab fragment heavy chain, Fd portion, ...
著者Gardberg, A.S, Dealwis, C.
登録日2007-08-21
公開日2007-10-16
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104, 2007
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
分子名称: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
著者Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
登録日2012-05-09
公開日2013-05-15
最終更新日2014-09-03
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
1MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE
著者Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
登録日1997-02-26
公開日1997-09-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
2MPA
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BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
分子名称: CADMIUM ION, CONJUGATE OF PORA P1.16 PEPTIDE WITH FLUORESCEIN, MN12H2 IGG2A-KAPPA, ...
著者Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
登録日1999-06-09
公開日1999-06-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
1CBV
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BU of 1cbv by Molmil
AN AUTOANTIBODY TO SINGLE-STRANDED DNA: COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF THE UNLIGANDED FAB AND A DEOXYNUCLEOTIDE-FAB COMPLEX
分子名称: DNA (5'-D(*TP*TP*T)-3'), PROTEIN (FAB (BV04-01) AUTOANTIBODY-HEAVY CHAIN), PROTEIN (FAB (BV04-01) AUTOANTIBODY-LIGHT CHAIN)
著者Herron, J.N, He, X.M, Ballard, D.W, Blier, P.R, Pace, P.E, Bothwell, A.L.M, Voss Junior, E.W, Edmundson, A.B.
登録日1993-03-16
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献An autoantibody to single-stranded DNA: comparison of the three-dimensional structures of the unliganded Fab and a deoxynucleotide-Fab complex.
Proteins, 11, 1991
2A1W
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BU of 2a1w by Molmil
Anti-cocaine antibody 7.5.21, crystal form I
分子名称: SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa
著者Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A.
登録日2005-06-21
公開日2005-06-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Flexibility Of Packing: Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
3EYU
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BU of 3eyu by Molmil
PFA1 Fab fragment complexed with Ror2(518-525)
分子名称: If kappa light chain, PFA1 Fab Heavy Chain, ROR2(518-525) peptide
著者Gardberg, A.S, Dealwis, C.G.
登録日2008-10-21
公開日2009-05-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of Abeta-related peptide--monoclonal antibody complexes.
Biochemistry, 48, 2009
2OJZ
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Anti-DNA antibody ED10
分子名称: Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
4OCY
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Fab for methotrexate (unbound apo)
分子名称: Fab ADD058 Heavy Chain, Fab ADD058 Light Chain
著者Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S.
登録日2014-01-09
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Water channel in the binding site of a high affinity anti-methotrexate antibody.
Biochemistry, 53, 2014
1PLG
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BU of 1plg by Molmil
EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID
分子名称: IGG2A=KAPPA=
著者Evans, S.V, Sigurskjold, B.W, Jennings, H.J, Brisson, J.-R, Tse, W.C, To, R, Altman, E, Frosch, M, Weisgerber, C, Kratzin, H, Klebert, S, Vaesen, M, Bitter-Suermann, D, Rose, D.R, Young, N.M, Bundle, D.R.
登録日1995-04-24
公開日1996-04-03
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.
Biochemistry, 34, 1995
1QFU
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BU of 1qfu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ...
著者Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M.
登録日1999-04-14
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999
1M71
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Crystal structure of a Monoclonal Fab Specific for Shigella Flexneri Y lipopolysaccharide
分子名称: heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6
著者Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A.
登録日2002-07-18
公開日2003-07-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodyanamics
Biochemistry, 41, 2002
4Q0X
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Crystal structure of non-neutralizing antibody in complex with Epitope II of HCV E2
分子名称: Envelope glycoprotein E2, mAb 12 heavy chain, mAb 12 light chain
著者Deng, L, Zhang, P.
登録日2014-04-02
公開日2014-07-09
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
3BQU
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Crystal Structure of the 2F5 Fab'-3H6 Fab Complex
分子名称: 2F5 Fab' heavy chain, 2F5 Fab' light chain, 3H6 Fab heavy chain, ...
著者Bryson, S, Julien, J.-P, Isenman, D.E, Kunert, R, Katinger, H, Pai, E.F.
登録日2007-12-20
公開日2008-10-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6.
J.Mol.Biol., 382, 2008
7A6C
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Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and elacridar
分子名称: CHOLESTEROL, If kappa light chain, MRK16 Fab-fragment heavy chain, ...
著者Nosol, K, Locher, K.P.
登録日2020-08-25
公開日2020-10-14
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Proc.Natl.Acad.Sci.USA, 117, 2020
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