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PDB: 12 件
6WN2
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BU of 6wn2 by Molmil
Tyrosyl t-RNA Synthetase Mutant from E.coli Complexed with sulfotyrosine
分子名称: O-SULFO-L-TYROSINE, SODIUM ION, SULFATE ION, ...
著者Beltran, D.G, Zhang, L.
登録日2020-04-22
公開日2020-09-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Functional genetic encoding of sulfotyrosine in mammalian cells.
Nat Commun, 11, 2020
2YXN
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BU of 2yxn by Molmil
Structual basis of azido-tyrosine recognition by engineered bacterial Tyrosyl-tRNA synthetase
分子名称: 3-AZIDO-L-TYROSINE, Tyrosyl-tRNA synthetase
著者Oki, K, Kobayashi, T, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-26
公開日2008-04-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Functional replacement of the endogenous tyrosyl-tRNA synthetase-tRNATyr pair by the archaeal tyrosine pair in Escherichia coli for genetic code expansion
Nucleic Acids Res., 38, 2010
6HB5
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BU of 6hb5 by Molmil
Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-cytidine
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Tyrosine--tRNA ligase, ...
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2018-08-09
公開日2019-04-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases.
Eur.J.Med.Chem., 173, 2019
6I5Y
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BU of 6i5y by Molmil
Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-adenosine
分子名称: 1,2-ETHANEDIOL, 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Tyrosine--tRNA ligase
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2018-11-15
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases.
Eur.J.Med.Chem., 173, 2019
6HB7
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BU of 6hb7 by Molmil
Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-N3-methyluridine
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Tyrosine--tRNA ligase, ...
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2018-08-09
公開日2019-04-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases.
Eur.J.Med.Chem., 173, 2019
6HB6
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BU of 6hb6 by Molmil
Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-uridine
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Tyrosine--tRNA ligase, ...
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2018-08-09
公開日2019-04-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases.
Eur.J.Med.Chem., 173, 2019
1WQ3
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BU of 1wq3 by Molmil
Escherichia coli tyrosyl-tRNA synthetase mutant complexed with 3-iodo-L-tyrosine
分子名称: 3-IODO-TYROSINE, Tyrosyl-tRNA synthetase
著者Kobayashi, T, Sakamoto, K, Nureki, O, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-09-20
公開日2005-01-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
1WQ4
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BU of 1wq4 by Molmil
Escherichia coli tyrosyl-tRNA synthetase mutant complexed with L-tyrosine
分子名称: TYROSINE, Tyrosyl-tRNA synthetase
著者Kobayashi, T, Sakamoto, K, Nureki, O, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-09-20
公開日2005-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
7AP3
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BU of 7ap3 by Molmil
Crystal structure of E. coli tyrosyl-tRNA synthetase in complex with TyrS7HMDDA
分子名称: SODIUM ION, Tyrosine--tRNA ligase, [(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2020-10-15
公開日2020-10-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors.
Molecules, 25, 2020
1X8X
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BU of 1x8x by Molmil
Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine
分子名称: SULFATE ION, TYROSINE, Tyrosyl-tRNA synthetase
著者Kobayashi, T, Takimura, T, Sekine, R, Kelly, V.P, Kamata, K, Sakamoto, K, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-08-19
公開日2005-01-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Snapshots of the KMSKS Loop Rearrangement for Amino Acid Activation by Bacterial Tyrosyl-tRNA Synthetase
J.MOL.BIOL., 346, 2005
1VBN
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BU of 1vbn by Molmil
Escherichia coli tyrosyl-tRNA synthetase mutant complexed with Tyr-AMS
分子名称: 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, Tyrosyl-tRNA synthetase
著者Kobayashi, T, Sakamoto, K, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-02-27
公開日2005-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion
Proc.Natl.Acad.Sci.USA, 102, 2005
1VBM
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BU of 1vbm by Molmil
Crystal structure of the Escherichia coli tyrosyl-tRNA synthetase complexed with Tyr-AMS
分子名称: 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, SULFATE ION, Tyrosyl-tRNA synthetase
著者Kobayashi, T, Sakamoto, K, Takimura, T, Kamata, K, Sekine, R, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-02-27
公開日2005-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase.
J.Mol.Biol., 346, 2005

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