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PDB: 9 件

6W9T
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BU of 6w9t by Molmil
Crystal structure of Neisseria meningitidis ClpP protease complex with small molecule activator ACP1-06
分子名称: ATP-dependent Clp protease proteolytic subunit, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide, POTASSIUM ION
著者Mabanglo, M.F, Houry, W.A.
登録日2020-03-23
公開日2020-12-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Development of Antibiotics That Dysregulate the Neisserial ClpP Protease.
Acs Infect Dis., 6, 2020
6NAQ
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BU of 6naq by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in Apo form
分子名称: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION
著者Houry, W.A, Mabanglo, M.F, Pai, E.F, Eger, B.T, Bryson, S.
登録日2018-12-06
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.022 Å)
主引用文献ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAY
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BU of 6nay by Molmil
Crystal structure of Neisseria meningitidis ClpP protease E31A+E58A activated double mutant
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Mabanglo, M.F, Houry, W.A.
登録日2018-12-06
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
5DKP
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BU of 5dkp by Molmil
Crystal Structure of N. meningitidis ClpP in complex with agonist ADEP A54556.
分子名称: ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION, SODIUM ION, ...
著者Goodreid, J.D, Janetzko, J, Santa Maria Jr, J.P, Wong, K, Leung, E, Eger, B.T, Bryson, S, Pai, E.F, Gray-Owen, S.D, Walker, S, Houry, W.A, Batey, R.A.
登録日2015-09-03
公開日2016-01-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Development and Characterization of Potent Cyclic Acyldepsipeptide Analogues with Increased Antimicrobial Activity.
J.Med.Chem., 59, 2016
6NAW
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BU of 6naw by Molmil
Crystal structure of Neisseria meningitidis ClpP E58A activated mutant
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Mabanglo, M.F, Houry, W.A.
登録日2018-12-06
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6NAH
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BU of 6nah by Molmil
Crystal structure of Neisseria meningitidis ClpP protease in complex with Acyldepsipeptide-14 (ADEP-14)
分子名称: ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide-14, OCTANOIC ACID (CAPRYLIC ACID)
著者Mabanglo, M.F, Houry, W.A.
登録日2018-12-05
公開日2019-11-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.
Commun Biol, 2, 2019
6VFX
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BU of 6vfx by Molmil
ClpXP from Neisseria meningitidis - Conformation B
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
著者Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
登録日2020-01-06
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
7KR2
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BU of 7kr2 by Molmil
ClpP from Neisseria meningitidis - Compressed conformation
分子名称: ATP-dependent Clp protease proteolytic subunit
著者Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E.
登録日2020-11-18
公開日2021-11-24
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A pH-Dependent Conformational Switch Controls N. meningitidis ClpP Protease Function
To Be Published
6VFS
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BU of 6vfs by Molmil
ClpXP from Neisseria meningitidis - Conformation A
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ...
著者Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E.
登録日2020-01-06
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020

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件を2024-07-10に公開中

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