9NPJ
 
 | | Structural studies of reaction hijacking inhibition of a malaria parasite aspartyl-tRNA synthetase. | | 分子名称: | 9-(5-O-{[(1R,2R)-2-amino-3-carboxy-1-hydroxypropyl]sulfamoyl}-beta-D-lyxofuranosyl)-2-chloro-9H-purin-6-amine, GLYCEROL, aspartate--tRNA ligase | | 著者 | Khandokar, Y, Ketprasit, K, Tai, C.W, Xie, S, Tilley, L, Griffin, M.D.W, Panjikar, S. | | 登録日 | 2025-03-11 | | 公開日 | 2025-06-04 | | 最終更新日 | 2025-07-23 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
Plos Pathog., 21, 2025
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9M5O
 | | Plasmodium vivax aspartyl-tRNA synthetase in complex with aspartyl sulfamoyl adenosine (Asp-AMS) Complex | | 分子名称: | 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, MAGNESIUM ION, aspartate--tRNA ligase | | 著者 | Sharma, V.K, Manickam, Y, Sharma, A, Bagale, S, Pradeepkumar, P.I. | | 登録日 | 2025-03-06 | | 公開日 | 2025-06-04 | | 最終更新日 | 2025-07-30 | | 実験手法 | X-RAY DIFFRACTION (1.839 Å) | | 主引用文献 | Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
Plos Pathog., 21, 2025
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9M5M
 | | Crystal structure of Plasmodium vivax aspartyl-tRNA synthetase (PvDRS) | | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, aspartate--tRNA ligase | | 著者 | Sharma, V.K, Manickam, Y, Bagale, S, Pradeepkumar, P.I, Sharma, A. | | 登録日 | 2025-03-06 | | 公開日 | 2025-06-04 | | 最終更新日 | 2025-07-30 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
Plos Pathog., 21, 2025
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9M5N
 | | Plasmodium vivax aspartyl-tRNA synthetase in complex with aspartyl-adenylate (Asp-AMP) Complex. | | 分子名称: | ACETATE ION, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, GLYCEROL, ... | | 著者 | Sharma, V.K, Manickam, Y, Sharma, A, Bagale, S, Pradeepkumar, P.I. | | 登録日 | 2025-03-06 | | 公開日 | 2025-06-04 | | 最終更新日 | 2025-07-30 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Natural product-mediated reaction hijacking mechanism validates Plasmodium aspartyl-tRNA synthetase as an antimalarial drug target.
Plos Pathog., 21, 2025
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