8J6R
| Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex | 分子名称: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | 登録日 | 2023-04-26 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
|
|
8J6Q
| Cryo-EM structure of the 3-HB and compound 9n-bound human HCAR2-Gi1 complex | 分子名称: | (3R)-3-hydroxybutanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, ... | 著者 | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | 登録日 | 2023-04-26 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
|
|
8J6P
| Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, ... | 著者 | Mao, C, Gao, M, Zang, S, Zhu, Y, Ma, X, Zhang, Y. | 登録日 | 2023-04-26 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Orthosteric and allosteric modulation of human HCAR2 signaling complex. Nat Commun, 14, 2023
|
|