9DOD
 
 | | Crystal structure of PRMT5:MEP50 in complex with PRT543 | | 分子名称: | 1,2-ETHANEDIOL, 7-[(3xi,5R)-5-C-(3,4-dichlorophenyl)-3-C-methyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Methylosome protein WDR77, ... | | 著者 | Leal, R.A, Pitis, P.M, Dou, Y, Lin, H, Wang, M, Xu, C. | | 登録日 | 2024-09-18 | | 公開日 | 2025-02-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Phase Ib study of PRT543, an oral protein arginine methyltransferase 5 (PRMT5) inhibitor, in patients with advanced splicing factor-mutant myeloid malignancies.
Leukemia, 39, 2025
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