PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

Structure of BACE complexed to compound 3a
分子名称:	(4S)-4-(2-AMINO-6-PHENOXYQUINAZOLIN-3(4H)-YL)-N,4-DICYCLOHEXYL-N-METHYLBUTANAMIDE, Beta-secretase 1
著者	Sharff, A.J.
登録日	2007-05-23
公開日	2007-08-14
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead. J.Med.Chem., 50, 2007

Structure of BACE complexed to compound 1
分子名称:	3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE, Beta-secretase 1
著者	Sharff, A.J.
登録日	2007-05-23
公開日	2007-08-14
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-Site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead. J.Med.Chem., 50, 2007