1SA5
| Rat protein farnesyltransferase complexed with FPP and BMS-214662 | 分子名称: | 3-BENZYL-1-(1H-IMIDAZOL-4-YLMETHYL)-4-(THIEN-2-YLSULFONYL)-2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPINE-7-CARBONITRILE, ACETIC ACID, FARNESYL DIPHOSPHATE, ... | 著者 | Reid, T.S, Beese, L.S. | 登録日 | 2004-02-06 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Biochemistry, 43, 2004
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1SA4
| human protein farnesyltransferase complexed with FPP and R115777 | 分子名称: | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... | 著者 | Reid, T.S, Beese, L.S. | 登録日 | 2004-02-06 | 公開日 | 2004-06-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity. Biochemistry, 43, 2004
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