6BVJ
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![BU of 6bvj by Molmil](/molmil-images/mine/6bvj) | Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | 5-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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6BVL
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![BU of 6bvl by Molmil](/molmil-images/mine/6bvl) | Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | FORMIC ACID, GLYCEROL, GTPase HRAS, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.748 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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6BVI
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![BU of 6bvi by Molmil](/molmil-images/mine/6bvi) | Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | 6-chloro-N-{1-[(5-chloro-1H-indol-3-yl)methyl]piperidin-4-yl}-L-tryptophanamide, FORMIC ACID, GLYCEROL, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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6BVM
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![BU of 6bvm by Molmil](/molmil-images/mine/6bvm) | Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | (2S)-2-amino-1-[(3aR,6aS)-5-[(5-chloro-1H-indol-3-yl)methyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-(1H-indol-3-yl)propan-1-one, FORMIC ACID, GLYCEROL, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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6BVK
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![BU of 6bvk by Molmil](/molmil-images/mine/6bvk) | Ras:SOS:Ras in complex with a small molecule activator | 分子名称: | FORMIC ACID, GLYCEROL, GTPase HRas, ... | 著者 | Phan, J, Abbott, J, Fesik, S.W. | 登録日 | 2017-12-13 | 公開日 | 2018-10-24 | 最終更新日 | 2019-05-01 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
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