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PDB: 1 件

9BFB
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Crystal structure of BRAF kinase domain with PF-07284890
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, N-{2-chloro-3-[(3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-fluorophenyl}-3-fluoropropane-1-sulfonamide, ...
著者Mou, T.-C.
登録日2024-04-17
公開日2024-08-14
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Identification of the Clinical Candidate PF-07284890 ( ARRY-461 ), a Highly Potent and Brain Penetrant BRAF Inhibitor for the Treatment of Cancer.
J.Med.Chem., 67, 2024

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件を2024-09-11に公開中

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