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PDB: 3 件

Crystal structure of human Sirt2 in complex with a triazole-based SirReal
分子名称:	(R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[5-[[3-[[1-(2-methoxyethyl)-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-1,3-thiazol-2-yl]ethanamide, ...
著者	Friedrich, F, Zhang, L, Schiedel, M, Einsle, O, Jung, M.
登録日	2023-04-28
公開日	2023-11-15
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem., 66, 2023

Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz317
分子名称:	1,2-ETHANEDIOL, 4-(acetamidomethyl)-N-hydroxybenzamide, Hdac6 protein, ...
著者	Tararina, M.A, Christianson, D.W.
登録日	2023-02-03
公開日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem., 66, 2023

Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with inhibitor Mz327
分子名称:	1,2-ETHANEDIOL, 4-[(N-butylpentanamido)methyl]-N-hydroxybenzamide, ETHANOL, ...
著者	Tararina, M.A, Christianson, D.W.
登録日	2023-02-03
公開日	2023-12-13
実験手法	X-RAY DIFFRACTION (1.766 Å)
主引用文献	Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation. J.Med.Chem., 66, 2023