PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892
分子名称:	5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine, Epidermal growth factor receptor
著者	Zhu, S.J.
登録日	2021-10-22
公開日	2022-06-08
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.507 Å)
主引用文献	Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022

The crystal structure of EGFR T790M/C797S with the inhibitor HC5476
分子名称:	25-chloro-11-(ethylsulfonyl)-44-morpholino-11H-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane, Epidermal growth factor receptor
著者	Zhu, S.J.
登録日	2021-10-22
公開日	2022-06-08
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.41 Å)
主引用文献	Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022