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PDB: 2 件

Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor
分子名称:	5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine, Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
著者	Howard, T.D, Ogg, D.T.
登録日	2021-12-14
公開日	2022-05-18
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.39 Å)
主引用文献	Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase gamma Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J.Med.Chem., 65, 2022

Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP
分子名称:	5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C)
著者	Howard, T.D, Ogg, D.T.
登録日	2022-01-05
公開日	2022-05-18
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase gamma Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J.Med.Chem., 65, 2022