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PDB: 1 件

4PGZ
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Structural basis of KIT activation by oncogenic mutations in the extracellular region reveals a zipper-like mechanism for ligand-dependent or oncogenic receptor tyrosine kinase activation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, Mast/stem cell growth factor receptor Kit
著者Reshetnyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J.
登録日2014-05-03
公開日2015-03-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer.
Mol.Cell, 57, 2015

239492

件を2025-07-30に公開中

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