8P81
 
 | | Crystal structure of human Cdk12/Cyclin K in complex with inhibitor SR-4835 | | 分子名称: | Cyclin-K, Cyclin-dependent kinase 12, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine | | 著者 | Anand, K, Schmitz, M, Geyer, M. | | 登録日 | 2023-05-31 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation.
J.Biol.Chem., 300, 2023
|
|
