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PDB: 5 件

8RDR
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BU of 8rdr by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8g
分子名称: (5~{S})-3-(2-nitrophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ...
著者Bischof, L, Hartmann, M.D.
登録日2023-12-08
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
8RDS
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BU of 8rds by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8i
分子名称: (5~{S})-3-(2-methoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ...
著者Bischof, L, Hartmann, M.D.
登録日2023-12-08
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
8RDT
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BU of 8rdt by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8j
分子名称: (5~{S})-3-(2,3,4-trimethoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ...
著者Bischof, L, Hartmann, M.D.
登録日2023-12-08
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
8RDQ
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BU of 8rdq by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8b
分子名称: (5S)-3-(2,4-dichlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ...
著者Bischof, L, Hartmann, M.D.
登録日2023-12-08
公開日2024-04-10
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
8RDP
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BU of 8rdp by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8a
分子名称: (5~{S})-3-(2-chlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ...
著者Bischof, L, Hartmann, M.D.
登録日2023-12-08
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024

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件を2024-06-26に公開中

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