PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

Crystal structure of pyrrolidine amide inhibitor [(3S)-3-(4-bromo-1H-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1H-pyrazol-5-yl]methanone (compound 35) in complex with KDM5A
分子名称:	Lysine-specific demethylase 5A, NICKEL (II) ION, SULFATE ION, ...
著者	Kiefer, J.R, Liang, J, Vinogradova, M.
登録日	2017-03-23
公開日	2017-05-10
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017

Crystal structure of selective pyrrolidine amide KDM5a inhibitor N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48)
分子名称:	Lysine-specific demethylase 5A, N-{(3R)-1-[3-(propan-2-yl)-1H-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide, NICKEL (II) ION, ...
著者	Kiefer, J.R, Liang, J, Vinogradova, M.
登録日	2017-03-23
公開日	2017-05-10
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.05 Å)
主引用文献	From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017