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PDB: 4 件

4JU4
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BU of 4ju4 by Molmil
Crystal structure of hcv ns5b polymerase in complex with compound 22
分子名称: 2-{[(4-bromo-2-fluorophenyl)sulfonyl]amino}-5-phenoxybenzoic acid, Genome polyprotein, MAGNESIUM ION
著者Coulombe, R.
登録日2013-03-24
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
Bioorg.Med.Chem.Lett., 23, 2013
4JU6
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BU of 4ju6 by Molmil
Crystal structure of hcv ns5b polymerase in complex with compound 24
分子名称: 2-{[(trans-4-methylcyclohexyl)carbonyl](propan-2-yl)amino}-5-phenoxybenzoic acid, Genome polyprotein, MAGNESIUM ION
著者Coulombe, R.
登録日2013-03-24
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
Bioorg.Med.Chem.Lett., 23, 2013
4JU7
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BU of 4ju7 by Molmil
Crystal structure of hcv ns5b polymerase in complex with compound 24
分子名称: 2-{[(trans-4-methylcyclohexyl)carbonyl](propan-2-yl)amino}-5-phenoxybenzoic acid, Genome polyprotein, MAGNESIUM ION
著者Coulombe, R.
登録日2013-03-24
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
Bioorg.Med.Chem.Lett., 23, 2013
4JU3
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BU of 4ju3 by Molmil
Crystal structure of hcv ns5b polymerase in complex with compound 8
分子名称: 5-(4-carboxyphenoxy)-2-{[(4-methylphenyl)sulfonyl]amino}benzoic acid, Genome polyprotein, MAGNESIUM ION
著者Coulombe, R.
登録日2013-03-24
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
Bioorg.Med.Chem.Lett., 23, 2013

223790

件を2024-08-14に公開中

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