PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 2 件

Identification of A New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-Dihydrothieno[3,2-d]pyrimidin-4(1H)-ones
分子名称:	Rho-associated protein kinase 2
著者	Hoffman, I.D.
登録日	2016-12-12
公開日	2017-03-29
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (3.15 Å)
主引用文献	Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones. Bioorg. Med. Chem., 25, 2017

Identification of A New Class of Potent Cdc7 Inhibitors Designed by Putative Pharmacophore Model: Synthesis and Biological Evaluation of 2,3-Dihydrothieno[3,2-d]pyrimidin-4(1H)-ones
分子名称:	(1s,4s)-4-(4-fluorophenyl)-4-hydroxy-6'-(5-methyl-1H-pyrazol-4-yl)-1'H-spiro[cyclohexane-1,2'-thieno[3,2-d]pyrimidin]-4'(3'H)-one, Rho-associated protein kinase 2
著者	Hoffman, I.D, Skene, R.J.
登録日	2016-12-12
公開日	2017-03-29
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (3.33 Å)
主引用文献	Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones. Bioorg. Med. Chem., 25, 2017