PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 3 件

Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX9486 (bezuclastinib) in the DFG-in state
分子名称:	4,5-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-3-carboxamide, Mast/stem cell growth factor receptor Kit
著者	Zhang, Y.
登録日	2020-10-21
公開日	2021-07-07
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.34 Å)
主引用文献	Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. Jama Oncol, 7, 2021

Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX8512 in the DFG-in state
分子名称:	2-phenyl-5-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, Mast/stem cell growth factor receptor Kit
著者	Zhang, Y.
登録日	2020-10-21
公開日	2021-07-07
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. Jama Oncol, 7, 2021

Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397
分子名称:	5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Mast/stem cell growth factor receptor Kit
著者	Zhang, Y.
登録日	2020-10-21
公開日	2021-07-07
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. Jama Oncol, 7, 2021