PDB: 52677 resultsInfo pagesStatus searchChemie searchBIRD

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5R1A	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 25, DMSO-free Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-12 Release date: 2020-06-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.73 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8QA2	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
5R1Q	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 41, DMSO-free Descriptor: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-12 Release date: 2020-06-03 Last modified: 2021-03-10 Method: X-RAY DIFFRACTION (1.86 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5R26	PanDDA analysis group deposition -- Endothiapepsin in complex with fragment F2X-Entry G02, DMSO-free Descriptor: Endothiapepsin, methyl [3-(aminomethyl)phenoxy]acetate Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-13 Release date: 2020-06-03 Last modified: 2020-07-08 Method: X-RAY DIFFRACTION (1.058 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8QA1	Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
5R2K	PanDDA analysis group deposition -- Auto-refined data of Endothiapepsin for ground state model 07, DMSO-Free Descriptor: Endothiapepsin Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-13 Release date: 2020-06-03 Last modified: 2020-07-08 Method: X-RAY DIFFRACTION (1.029 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8QA3	Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
5R30	PanDDA analysis group deposition -- Auto-refined data of Endothiapepsin for ground state model 24, DMSO-Free Descriptor: Endothiapepsin Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-13 Release date: 2020-06-03 Last modified: 2020-07-08 Method: X-RAY DIFFRACTION (1.038 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5R3G	PanDDA analysis group deposition -- Auto-refined data of Endothiapepsin for ground state model 40, DMSO-Free Descriptor: Endothiapepsin Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-13 Release date: 2020-06-03 Last modified: 2020-07-08 Method: X-RAY DIFFRACTION (1.106 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5R3X	PanDDA analysis group deposition -- Auto-refined data of Endothiapepsin for ground state model 57, DMSO-Free Descriptor: Endothiapepsin Authors: Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. Deposit date: 2020-02-13 Release date: 2020-06-03 Last modified: 2020-07-08 Method: X-RAY DIFFRACTION (1.165 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8QA0	Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation Descriptor: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE Authors: Brotherton, D.H, Cameron, A.D. Deposit date: 2023-08-22 Release date: 2024-06-12 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2. Elife, 13, 2024
5RC0	PanDDA analysis group deposition -- Endothiapepsin changed state model for fragment F2X-Entry Library E06a Descriptor: (3-endo)-8-benzyl-8-azabicyclo[3.2.1]octan-3-ol, ACETATE ION, DIMETHYL SULFOXIDE, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-03-24 Release date: 2020-06-03 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (1.03 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5RCD	PanDDA analysis group deposition -- Endothiapepsin changed state model for fragment F2X-Entry Library H03a Descriptor: ACETATE ION, DIMETHYL SULFOXIDE, Endothiapepsin, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-03-24 Release date: 2020-06-03 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (1.02 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
6Q2I	Solution state NMR structures of the RNA recognition motif (RRM) domain of human CstF-64 Descriptor: Cleavage stimulation factor subunit 2 Authors: Latham, M.P, Masoumzadeh, E. Deposit date: 2019-08-08 Release date: 2020-08-12 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans. Nucleic Acids Res., 48, 2020
5Y4O	Cryo-EM structure of MscS channel, YnaI Descriptor: Low conductance mechanosensitive channel YnaI Authors: Zhang, Y, Yu, J. Deposit date: 2017-08-04 Release date: 2019-03-20 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: A binding-block ion selective mechanism revealed by a Na/K selective channel. Protein Cell, 9, 2018
5RCT	PanDDA analysis group deposition -- Endothiapepsin ground state model 15 Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, Endothiapepsin, ... Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-03-24 Release date: 2020-06-03 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (1.01 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
5RD9	PanDDA analysis group deposition -- Endothiapepsin ground state model 31 Descriptor: Endothiapepsin Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-03-24 Release date: 2020-06-03 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (1.11 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
6PV1	Backbone-modified variant of zinc finger 2 from the transcription factor Sp1 DNA binding domain: Aib in the metal-binding turn Descriptor: Transcription factor Sp1, ZINC ION Authors: Rao, S.R, Horne, W.S. Deposit date: 2019-07-19 Release date: 2020-06-24 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Proteomimetic Zinc Finger Domains with Modified Metal-binding beta-Turns. Pept Sci (Hoboken), 112, 2020
5RDS	PanDDA analysis group deposition -- Endothiapepsin ground state model 49 Descriptor: Endothiapepsin Authors: Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G. Deposit date: 2020-03-24 Release date: 2020-06-03 Last modified: 2020-06-17 Method: X-RAY DIFFRACTION (0.97 Å) Cite: F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
6Q1G	Human antibody H1244 of the human antibody lineage 652 Descriptor: GLYCEROL, H1244 Fab heavy chain, H1244 Fab lambda chain Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-04 Release date: 2019-12-18 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
5YKG	Structure of pancreatic ATP-sensitive potassium channel bound with glibenclamide and ATPgammaS (Class2 at 4.57A) Descriptor: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Chen, L, Wu, J.X. Deposit date: 2017-10-14 Release date: 2018-04-18 Last modified: 2018-06-13 Method: ELECTRON MICROSCOPY (4.57 Å) Cite: Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels. Protein Cell, 9, 2018
6Q0K	Structure of a MAPK pathway complex Descriptor: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase B-raf Authors: Park, E, Rawson, S, Jeon, H, Eck, M.J. Deposit date: 2019-08-01 Release date: 2019-10-09 Last modified: 2020-04-22 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
5XZJ	Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, C96T/AB5 Descriptor: CHLORIDE ION, HEME C, Soluble cytochrome b562, ... Authors: Song, W.J, Tezcan, F.A. Deposit date: 2017-07-12 Release date: 2017-12-20 Last modified: 2022-03-23 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Importance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases. J. Am. Chem. Soc., 139, 2017
5Y1Z	Crystal structure of ZMYND8 PHD-BROMO-PWWP tandem in complex with Drebrin ADF-H domain Descriptor: Drebrin, GLYCEROL, Protein kinase C-binding protein 1, ... Authors: Yao, N, Li, J, Liu, H, Wan, J, Liu, W, Zhang, M. Deposit date: 2017-07-22 Release date: 2017-10-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.676 Å) Cite: The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin Structure, 25, 2017
8VQC	Structure of the voltage-gated sodium channel NavPas from American Cockroach Periplaneta Americana in complex with scorpion alpha-toxin LqhaIT Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-insect toxin LqhaIT, ... Authors: Phulera, S, Khoshouei, M, Whicher, J, Weihofen, W.A. Deposit date: 2024-01-18 Release date: 2024-09-04 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Scorpion alpha-toxin Lqh alpha IT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels. Structure, 2024

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