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3LDV
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BU of 3ldv by Molmil
1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961
Descriptor: CHLORIDE ION, MAGNESIUM ION, Orotidine 5'-phosphate decarboxylase
Authors:Halavaty, A.S, Shuvalova, L, Minasov, G, Dubrovska, I, Winsor, J, Glass, E.M, Peterson, S.N, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-01-13
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961
To be Published
1SKU
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BU of 1sku by Molmil
E. coli Aspartate Transcarbamylase 240's Loop Mutant (K244N)
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ...
Authors:Alam, N, Stieglitz, K.A, Caban, M.D, Gourinath, S, Tsuruta, H, Kantrowitz, E.R.
Deposit date:2004-03-05
Release date:2004-03-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase.
J.Biol.Chem., 279, 2004
1VQT
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BU of 1vqt by Molmil
Crystal structure of Orotidine 5'-phosphate decarboxylase (TM0332) from Thermotoga maritima at 2.00 A resolution
Descriptor: 1,2-ETHANEDIOL, Orotidine 5'-phosphate decarboxylase
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2005-01-04
Release date:2005-01-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Orotidine 5'-phosphate decarboxylase (TM0332) from Thermotoga maritima at 2.00 A resolution
To be published
1NBE
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BU of 1nbe by Molmil
ASPARTATE TRANSCARBAMOYLASE REGULATORY CHAIN MUTANT (T82A)
Descriptor: ASPARTATE TRANSCARBAMOYLASE, D-MALATE, ZINC ION
Authors:Williams, M.K, Stec, B, Kantrowitz, E.R.
Deposit date:1998-04-25
Release date:1998-10-14
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A single mutation in the regulatory chain of Escherichia coli aspartate transcarbamoylase results in an extreme T-state structure.
J.Mol.Biol., 281, 1998
7T24
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BU of 7t24 by Molmil
Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa
Descriptor: Adenylosuccinate lyase, IMIDAZOLE, ISOPROPYL ALCOHOL
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-03
Release date:2021-12-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa
to be published
7T29
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Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-12-03
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Adenylosuccinate lyase (ASL) from Pseudomonas aeruginosa complexed with AMP
to be published
4EEI
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BU of 4eei by Molmil
Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, ...
Authors:Maltseva, N, Kim, Y, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-03-28
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.921 Å)
Cite:Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
To be Published
1ORO
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BU of 1oro by Molmil
A FLEXIBLE LOOP AT THE DIMER INTERFACE IS A PART OF THE ACTIVE SITE OF THE ADJACENT MONOMER OF ESCHERICHIA COLI OROTATE PHOSPHORIBOSYLTRANSFERASE
Descriptor: OROTATE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION
Authors:Henriksen, A, Aghajari, N, Jensen, K.F, Gajhede, M.
Deposit date:1995-09-11
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase.
Biochemistry, 35, 1996
2YYT
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BU of 2yyt by Molmil
Crystal structure of uncharacterized conserved protein from Geobacillus kaustophilus
Descriptor: Orotidine 5'-phosphate decarboxylase
Authors:Kanagawa, M, Baba, S, Nakamura, Y, Bessho, Y, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-02
Release date:2007-11-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of uncharacterized conserved protein from Geobacillus kaustophilus
To be Published
7B1O
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BU of 7b1o by Molmil
Crystal structure of the indoleamine 2,3-dioxygenase 1 (IDO1) in complex with compound 22
Descriptor: 4-chloranyl-N-[(1R)-1-[(1S,5R)-3-quinolin-4-yloxy-6-bicyclo[3.1.0]hexanyl]propyl]benzamide, Indoleamine 2,3-dioxygenase 1
Authors:Lammens, A, Krapp, S, Lewis, R.T, Hamilton, M.M.
Deposit date:2020-11-25
Release date:2021-09-29
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Discovery of IACS-9779 and IACS-70465 as Potent Inhibitors Targeting Indoleamine 2,3-Dioxygenase 1 (IDO1) Apoenzyme.
J.Med.Chem., 64, 2021
2ZZ7
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Orotidine Monophosphate Decarboxylase K72A mutant complexed with BMP (produced from 6-Iodo-UMP)
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
1OVD
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BU of 1ovd by Molmil
THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE
Descriptor: DIHYDROOROTATE DEHYDROGENASE A, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Norager, S, Arent, S, Bjornberg, O, Ottosen, M, Lo Leggio, L, Jensen, K.F, Larsen, S.
Deposit date:2003-03-26
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function.
J.Biol.Chem., 278, 2003
2ZZ3
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Covalent complex of orotidine monophosphate decarboxylase D70A mutant from M. thermoautotrophicus with 6-cyano-UMP
Descriptor: 6-cyanouridine 5'-phosphate, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
2ZZ5
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Orotidine Monophosphate Deacarboxylase D70A/K72A double mutant from M. thermoautotrophicum complexed with 6- cyano-UMP
Descriptor: 6-cyanouridine 5'-phosphate, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
4EKN
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BU of 4ekn by Molmil
Structure of the catalytic chain of Methanococcus jannaschii Aspartate Transcarbamoylase in a hexagonal crystal form
Descriptor: Aspartate carbamoyltransferase, GLYCEROL, POTASSIUM ION, ...
Authors:Vitali, J.
Deposit date:2012-04-09
Release date:2012-05-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4996 Å)
Cite:Structure of the catalytic chain of Methanococcus jannaschii aspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzyme.
Acta Crystallogr.,Sect.F, 68, 2012
2ZZ4
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BU of 2zz4 by Molmil
Covalent complex of orotidine monophosphate decarboxylase D75N mutant from M. thermoautotrophicum with 6-cyano-UMP
Descriptor: 6-cyanouridine 5'-phosphate, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
2ZZ2
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BU of 2zz2 by Molmil
Orotidine Monophosphate Decarboxylase K72A mutant from M. thermoautotrophicum complexed with 6-cyano-UMP
Descriptor: 6-cyanouridine 5'-phosphate, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
2ZZ1
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Snapshot of the reaction from 6-CN-UMP to BMP catalyzed by Orotidine Monophosphate Deacarboxylase from M. thermoautotrophicum
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, 6-cyanouridine 5'-phosphate, GLYCEROL, ...
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
4DF1
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Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, NICKEL (II) ION, Orotidine 5'-phosphate decarboxylase
Authors:Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C.
Deposit date:2012-01-22
Release date:2013-01-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP
To be Published
4E2F
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BU of 4e2f by Molmil
Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state
Descriptor: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
Authors:Guo, W, Kantrowitz, E.R.
Deposit date:2012-03-08
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase.
Proc.Natl.Acad.Sci.USA, 109, 2012
6YF3
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BU of 6yf3 by Molmil
FKBP12 in complex with the BMP potentiator compound 10 at 1.00A resolution
Descriptor: (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S},23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1,14,23-tris(oxidanyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone, CADMIUM ION, CHLORIDE ION, ...
Authors:Kallen, J.
Deposit date:2020-03-25
Release date:2021-03-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1 Å)
Cite:Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Cell Chem Biol, 28, 2021
3BGJ
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BU of 3bgj by Molmil
Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP
Descriptor: GLYCEROL, URIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase
Authors:Liu, Y, Tang, H.L, Bello, A.M, Devalla, S, Kotra, L.P, Pai, E.F.
Deposit date:2007-11-26
Release date:2008-11-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Human Orotidine 5'-monophosphate Decarboxylase Covalently Modified by 6-iodo-UMP
To be Published
3BGG
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BU of 3bgg by Molmil
Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, Uridine 5'-monophosphate synthase
Authors:Liu, Y, Tang, H.L, Wang, X.Y, Kotra, L.P, Pai, E.F.
Deposit date:2007-11-26
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of Human Orotidine 5'-monophosphate Decarboxylase complexed with BMP
To be Published
2ZA3
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Crystal Structure of orotidine 5'-monophosphate decarboxylase complexed with uridine 5'-monophosphate from P.falciparum
Descriptor: Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE
Authors:Tokuoka, K, Inoue, T.
Deposit date:2007-09-26
Release date:2007-12-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for the Decarboxylation of Orotidine 5'-Monophosphate (OMP) by Plasmodium Falciparum OMP Decarboxylase
J.Biochem.(Tokyo), 143, 2008
2ZA1
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Crystal Structure of orotidine 5'-monophosphate decarboxylase complexed with orotidine 5'-monophosphate from P.falciparum
Descriptor: OROTIDINE-5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase
Authors:Tokuoka, K, Inoue, T.
Deposit date:2007-09-26
Release date:2007-12-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis for the Decarboxylation of Orotidine 5'-Monophosphate (OMP) by Plasmodium Falciparum OMP Decarboxylase
J.BIOCHEM.(TOKYO), 143, 2008

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