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6HFH	Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.44871271 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFR	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.29949379 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG2	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to fluoroorotate Descriptor: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFP	Human dihydroorotase mutant F1563T co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.1982286 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG3	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop, bound to dihydroorotate Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.97 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFK	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 6.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.459144 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6JVB	Crystal Structure of Human CRMP2 1-532, AGE-modified Descriptor: Dihydropyrimidinase-related protein 2 Authors: Jiang, X, Ogawa, T, Hirokawa, N. Deposit date: 2019-04-16 Release date: 2019-10-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis. Life Sci Alliance, 2, 2019
6HFE	Human dihydroorotase mutant F1563T apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.47997439 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFU	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.3997103 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFL	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.0 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HG1	Hybrid dihydroorotase domain of human CAD with E. coli flexible loop in apo state Descriptor: CAD protein,Dihydroorotase,CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Del Cano-Ochoa, F. Deposit date: 2018-08-22 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFN	Human dihydroorotase mutant F1563L co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.44965148 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFI	Human dihydroorotase mutant F1563A apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.45994723 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFD	Human dihydroorotase mutant F1563L apo structure Descriptor: CAD protein, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.869968 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFJ	Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5 Descriptor: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD protein, FORMIC ACID, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6HFS	Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 6.5 Descriptor: CAD protein, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ... Authors: Ramon-Maiques, S, Grande Garcia, A. Deposit date: 2018-08-21 Release date: 2018-10-24 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.34904516 Å) Cite: Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293, 2018
6JV9	Crystal Structure of Human CRMP2 1-532, unmodified Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydropyrimidinase-related protein 2, ... Authors: Jiang, X, Ogawa, T, Hirokawa, N. Deposit date: 2019-04-16 Release date: 2019-10-09 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis. Life Sci Alliance, 2, 2019
1GKP	D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HYDANTOINASE, SULFATE ION, ... Authors: Abendroth, J, Niefind, K, Schomburg, D. Deposit date: 2001-08-20 Release date: 2002-06-27 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (1.295 Å) Cite: X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
1GKR	L-Hydantoinase (Dihydropyrimidinase) from Arthrobacter aurescens Descriptor: NON-ATP DEPENDENT L-SELECTIVE HYDANTOINASE, ZINC ION Authors: Abendroth, J, Niefind, K, Schomburg, D. Deposit date: 2001-08-20 Release date: 2002-07-25 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The structure of L-hydantoinase from Arthobacter aurescens leads to an understanding of dihydropyrimidinase substrate and enantio specificity. Biochemistry, 41, 2002
1GKQ	D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group P212121 Descriptor: HYDANTOINASE, ZINC ION Authors: Abendroth, J, Niefind, K, Schomburg, D. Deposit date: 2001-08-20 Release date: 2002-06-27 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
4BKN	Human Dihydropyrimidinase-related protein 3 (DPYSL3) Descriptor: DIHYDROPYRIMIDINASE-RELATED PROTEIN 3 Authors: Mathea, S, Elkins, J.M, Alegre-Abarrategui, J, Shrestha, L, Burgess-Brown, N, Puranik, S, Coutandin, D, Bradley, A, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A, Knapp, S. Deposit date: 2013-04-26 Release date: 2013-05-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of Dpysl3 To be Published
4B3Z	Structure of the human collapsin response mediator protein-1, a lung cancer suppressor Descriptor: DIHYDROPYRIMIDINASE-RELATED PROTEIN 1 Authors: Liu, S.H, Lin, Y.H, Huang, S.F, Niou, Y.K, Huang, L.L, Chen, Y.J. Deposit date: 2012-07-27 Release date: 2013-08-07 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Structure of Human Collapsin Response Mediator Protein 1: A Possible Role of its C-Terminal Tail. Acta Crystallogr.,Sect.F, 71, 2015
4B92	Crystal structure of truncated human CRMP-5 soaked with Zn Descriptor: DIHYDROPYRIMIDINASE-RELATED PROTEIN 5, ZINC ION Authors: Ponnusamy, R, Lohkamp, B. Deposit date: 2012-08-31 Release date: 2013-02-13 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Insights Into the Oligomerization of Crmps: Crystal Structure of Human Collapsin Response Mediator Protein 5. J.Neurochem., 125, 2013
4C6C	Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from HEK293 cells. Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. Deposit date: 2013-09-18 Release date: 2014-01-08 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.451 Å) Cite: Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014
4C6O	Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 6.0 Descriptor: CAD PROTEIN, FORMIC ACID, ZINC ION Authors: Ramon-Maiques, S, Lallous, N, Grande-Garcia, A. Deposit date: 2013-09-18 Release date: 2014-02-05 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad. Structure, 22, 2014

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