2J28
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![BU of 2j28 by Molmil](/molmil-images/mine/2j28) | MODEL OF E. COLI SRP BOUND TO 70S RNCS | Descriptor: | 23S RIBOSOMAL RNA, 4.5S SIGNAL RECOGNITION PARTICLE RNA, 50S ribosomal protein L11, ... | Authors: | Halic, M, Blau, M, Becker, T, Mielke, T, Pool, M.R, Wild, K, Sinning, I, Beckmann, R. | Deposit date: | 2006-08-16 | Release date: | 2006-11-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Following the Signal Sequence from Ribosomal Tunnel Exit to Signal Recognition Particle Nature, 444, 2006
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6XZ9
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![BU of 6xz9 by Molmil](/molmil-images/mine/6xz9) | Structure of aldosterone synthase (CYP11B2) in complex with 5-chloro-3,3-dimethyl-2-[5-[1-(1-methylpyrazole-4-carbonyl)azetidin-3-yl]oxy-3-pyridyl]isoindolin-1-one | Descriptor: | 5-chloranyl-3,3-dimethyl-2-[5-[1-(1-methylpyrazol-4-yl)carbonylazetidin-3-yl]oxypyridin-3-yl]isoindol-1-one, Cytochrome P450 11B2, mitochondrial, ... | Authors: | Kuglstatter, A, Joseph, C, Benz, J. | Deposit date: | 2020-02-03 | Release date: | 2020-06-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors. J.Med.Chem., 63, 2020
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2AXK
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![BU of 2axk by Molmil](/molmil-images/mine/2axk) | Solution structure of discrepin, a scorpion venom toxin blocking K+ channels. | Descriptor: | discrepin | Authors: | Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M. | Deposit date: | 2005-09-05 | Release date: | 2006-06-20 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily. Biochemistry, 45, 2006
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2AMH
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2B24
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![BU of 2b24 by Molmil](/molmil-images/mine/2b24) | Crystal structure of naphthalene 1,2-dioxygenase from Rhodococcus sp. bound to indole | Descriptor: | FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, INDOLE, ... | Authors: | Gakhar, L, Malik, Z.A, Allen, C.C, Lipscomb, D.A, Larkin, M.J, Ramaswamy, S. | Deposit date: | 2005-09-16 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure and Increased Thermostability of Rhodococcus sp. Naphthalene 1,2-Dioxygenase. J.Bacteriol., 187, 2005
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2IDQ
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![BU of 2idq by Molmil](/molmil-images/mine/2idq) | Structure of M98A mutant of amicyanin, Cu(II) | Descriptor: | Amicyanin, COPPER (II) ION, PHOSPHATE ION | Authors: | Carrell, C.J, Ma, J.K, Antholine, W, Hosler, J.P, Mathews, F.S, Davidson, V.L. | Deposit date: | 2006-09-15 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Generation of Novel Copper Sites by Mutation of the Axial Ligand of Amicyanin. Atomic Resolution Structures and Spectroscopic Properties Biochemistry, 46, 2007
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6XU3
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![BU of 6xu3 by Molmil](/molmil-images/mine/6xu3) | (R)-selective amine transaminase from Shinella sp. | Descriptor: | 3-AMINOBENZOIC ACID, CHLORIDE ION, Class IV aminotransferase, ... | Authors: | Telzerow, A, Hakansson, M, Steiner, K. | Deposit date: | 2020-01-17 | Release date: | 2020-12-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members. Chembiochem, 22, 2021
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2AVV
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![BU of 2avv by Molmil](/molmil-images/mine/2avv) | Kinetics, stability, and structural changes in high resolution crystal structures of HIV-1 protease with drug resistant mutations L24I, I50V, and G73S | Descriptor: | ACETIC ACID, CHLORIDE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, ... | Authors: | Liu, F, Boross, P.I, Wang, Y.F, Tozser, J, Louis, J.M, Harrison, R.W, Weber, I.T. | Deposit date: | 2005-08-30 | Release date: | 2006-01-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S. J.Mol.Biol., 354, 2005
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7S3O
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![BU of 7s3o by Molmil](/molmil-images/mine/7s3o) | NMR Solution Structure of hGal(2-12)KK, a solubility-tagged truncation of the human neuropeptide galanin | Descriptor: | Galanin | Authors: | Kraichely, K.N, Clinkscales, S.E, Parnham, S, Giuliano, M.W. | Deposit date: | 2021-09-07 | Release date: | 2022-05-25 | Last modified: | 2022-07-06 | Method: | SOLUTION NMR | Cite: | Minimal Increments of Hydrophobic Collapse within the N-Terminus of the Neuropeptide Galanin. Biochemistry, 61, 2022
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7S3Q
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![BU of 7s3q by Molmil](/molmil-images/mine/7s3q) | NMR Solution Structure of hGal(1-12)KK, a solubility-tagged truncation of the human neuropeptide galanin | Descriptor: | Galanin | Authors: | Kraichely, K.N, Hendy, C.M, Parnham, S, Giuliano, M.W. | Deposit date: | 2021-09-08 | Release date: | 2022-05-25 | Last modified: | 2022-07-06 | Method: | SOLUTION NMR | Cite: | Minimal Increments of Hydrophobic Collapse within the N-Terminus of the Neuropeptide Galanin. Biochemistry, 61, 2022
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7NPH
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![BU of 7nph by Molmil](/molmil-images/mine/7nph) | Crystal structure of Mycobacterium tuberculosis ArgC in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid | Descriptor: | 5-methoxy-1,3-benzoxazole-2-carboxylic acid, N-acetyl-gamma-glutamyl-phosphate reductase, PHOSPHATE ION | Authors: | Gupta, P, Mendes, V, Blundell, T.L. | Deposit date: | 2021-02-26 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
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7S3R
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![BU of 7s3r by Molmil](/molmil-images/mine/7s3r) | NMR Solution Structure of hGal(1-12)KK, a solubility-tagged truncation of the human neuropeptide galanin | Descriptor: | Galanin | Authors: | Kraichely, K.N, Mendoza, E.A, Parnham, S, Giuliano, M.W. | Deposit date: | 2021-09-08 | Release date: | 2022-05-25 | Last modified: | 2022-07-06 | Method: | SOLUTION NMR | Cite: | Minimal Increments of Hydrophobic Collapse within the N-Terminus of the Neuropeptide Galanin. Biochemistry, 61, 2022
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7NOT
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![BU of 7not by Molmil](/molmil-images/mine/7not) | Crystal structure of Mycobacterium tuberculosis ArgC in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-Methoxy-3-indoleacetic acid | Descriptor: | (5-methoxy-1H-indol-3-yl)acetic acid, N-acetyl-gamma-glutamyl-phosphate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Gupta, P, Mendes, V, Blundell, T.L. | Deposit date: | 2021-02-25 | Release date: | 2021-06-30 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
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2HPD
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![BU of 2hpd by Molmil](/molmil-images/mine/2hpd) | CRYSTAL STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450'S | Descriptor: | CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ravichandran, K.G, Boddupalli, S.S, Hasemann, C.A, Peterson, J.A, Deisenhofer, J. | Deposit date: | 1993-09-16 | Release date: | 1993-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's. Science, 261, 1993
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2AXU
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![BU of 2axu by Molmil](/molmil-images/mine/2axu) | Structure of PrgX | Descriptor: | PrgX | Authors: | Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A. | Deposit date: | 2005-09-06 | Release date: | 2005-12-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis. Proc.Natl.Acad.Sci.Usa, 102, 2005
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7N6E
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![BU of 7n6e by Molmil](/molmil-images/mine/7n6e) | TCR peptide HLA-A2 complex | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ... | Authors: | Chaurasia, P, Rossjohn, J, Petersen, J. | Deposit date: | 2021-06-08 | Release date: | 2021-07-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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2IJ4
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![BU of 2ij4 by Molmil](/molmil-images/mine/2ij4) | Structure of the A264K mutant of cytochrome P450 BM3 | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 | Authors: | Toogood, H.S, Leys, D. | Deposit date: | 2006-09-29 | Release date: | 2006-11-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3. J.Biol.Chem., 282, 2007
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2B9E
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![BU of 2b9e by Molmil](/molmil-images/mine/2b9e) | Human NSUN5 protein | Descriptor: | NOL1/NOP2/Sun domain family, member 5 isoform 2, S-ADENOSYLMETHIONINE | Authors: | Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2005-10-11 | Release date: | 2005-10-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The Crystal Structure of Human NSUN5 protein in complex with
S-adenosyl-L-methionine To be Published
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2AJD
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![BU of 2ajd by Molmil](/molmil-images/mine/2ajd) | Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro) | Descriptor: | (2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Engel, M, Hoffmann, T, Manhart, S, Heiser, U, Chambre, S, Huber, R, Demuth, H.U, Bode, W. | Deposit date: | 2005-08-01 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV. J.Mol.Biol., 355, 2006
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2IMQ
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![BU of 2imq by Molmil](/molmil-images/mine/2imq) | Crystal structure of ferrous cimex nitrophorin | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Salivary nitrophorin | Authors: | Weichsel, A, Montfort, W.R. | Deposit date: | 2006-10-04 | Release date: | 2007-08-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystallographic and spectroscopic characterization of ferrous complexes of cimex nitrophorin, a heme-thiolate protein from the bedbug To be Published
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6XL9
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![BU of 6xl9 by Molmil](/molmil-images/mine/6xl9) | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt) | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Yang, Y, Liu, C, Shi, W, Liu, B. | Deposit date: | 2020-06-28 | Release date: | 2021-04-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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2BBK
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6XLJ
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![BU of 6xlj by Molmil](/molmil-images/mine/6xlj) | Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt) | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Yang, Y, Liu, C, Liu, B. | Deposit date: | 2020-06-28 | Release date: | 2021-04-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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6XL5
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![BU of 6xl5 by Molmil](/molmil-images/mine/6xl5) | Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo) | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Yang, Y, Liu, C, Liu, B. | Deposit date: | 2020-06-28 | Release date: | 2021-04-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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6XLN
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![BU of 6xln by Molmil](/molmil-images/mine/6xln) | Cryo-EM structure of E. coli RNAP-DNA elongation complex 2 (RDe2) in EcmrR-dependent transcription | Descriptor: | 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Yang, Y, Liu, C, Liu, B. | Deposit date: | 2020-06-28 | Release date: | 2021-04-07 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural visualization of transcription activated by a multidrug-sensing MerR family regulator. Nat Commun, 12, 2021
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