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7FTR	Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-N-(4-acetylphenyl)-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide Descriptor: (2Z)-N-(4-acetylphenyl)-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Canesso, R, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTS	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-N-[[2-fluoro-5-(1-methylpyrazol-4-yl)phenyl]methyl]-2-hydroxybenzamide Descriptor: 5-bromo-N-{[(5P)-2-fluoro-5-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-2-hydroxybenzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.215 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTT	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-N-[[2-fluoro-5-(1-methylpyrazol-4-yl)phenyl]methyl]-2-hydroxybenzamide Descriptor: 5-bromo-N-{[(5P)-2-fluoro-5-(1-methyl-1H-pyrazol-4-yl)phenyl]methyl}-2-hydroxybenzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.235 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FTV	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-bromo-2-hydroxy-N-(quinolin-6-ylmethyl)benzamide Descriptor: 5-bromo-2-hydroxy-N-[(quinolin-6-yl)methyl]benzamide, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.875 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU0	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-phenylphenyl)methylamino]-5-(trifluoromethyl)-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-{[([1,1'-biphenyl]-4-yl)methyl]amino}-5-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.969 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU2	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-5-fluoro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Zhou, C, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU3	Crystal Structure of human cyclic GMP-AMP synthase in complex with 8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid Descriptor: (2P)-8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Brunner, M, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.822 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU6	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-benzyl-6-(2-chloro-4-methylphenyl)indazole-4-carboxylic acid Descriptor: (6M)-2-benzyl-6-(2-chloro-4-methylphenyl)-2H-indazole-4-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.37 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU8	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.718 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FU9	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.668 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUA	Crystal Structure of human cyclic GMP-AMP synthase in complex with phosphate Descriptor: Cyclic GMP-AMP synthase, PHOSPHATE ION, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.444 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUB	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-(pyridin-4-ylmethyl)benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-4-methylphenyl)-1-[(pyridin-4-yl)methyl]-1H-benzimidazole-7-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.981 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUF	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.919 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUG	Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.106 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUH	Crystal Structure of human cyclic GMP-AMP synthase in complex with phosphate Descriptor: Cyclic GMP-AMP synthase, PHOSPHATE ION, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.944 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUI	Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-2-cyano-N-[4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide Descriptor: (2Z)-2-cyano-N-[(4P)-4-(3-fluorophenyl)-5-(methanesulfonyl)pyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUK	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-(2-phenylethyl)benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-4-methylphenyl)-1-(2-phenylethyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.606 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUL	Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-[3-(methanesulfonamido)propyl]benzimidazole-4-carboxylic acid Descriptor: (5M)-5-(2-chloro-4-methylphenyl)-1-{3-[(methanesulfonyl)amino]propyl}-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.296 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUM	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-2-[(4-benzylpiperazin-1-yl)methyl]-5-(2-chloro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUN	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid Descriptor: (5M)-2-[(4-benzylpiperazin-1-yl)methyl]-5-(2-chloro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, CHLORIDE ION, Cyclic GMP-AMP synthase, ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
7FUO	Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chlorophenyl)methylamino]-5-[(2-fluoroanilino)methyl]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one Descriptor: (8R)-2-{[(2-chlorophenyl)methyl]amino}-5-[(2-fluoroanilino)methyl][1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Brunner, M, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
6PJW	Adenylate kinase from Methanococcus igneus - AMP bound form Descriptor: ADENOSINE MONOPHOSPHATE, Adenylate kinase, MAGNESIUM ION Authors: Moon, S, Kim, J, Olmos, J.L, Bae, E, Phillips Jr, G.N. Deposit date: 2019-06-28 Release date: 2020-01-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Adenylate kinase from Methanococcus igneus - AMP bound form To Be Published
3R6S	Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, HEXANE-1,6-DIOL, transcription regulator Authors: Jungwirth, B, Pojer, F. Deposit date: 2011-03-22 Release date: 2012-03-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP To be Published
8SF3	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (AMP, Acetate and CoA bound) Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-04-10 Release date: 2023-04-19 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (AMP and CoA bound) To be published
5OE5	Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 3) Descriptor: 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate--CoA ligase, DI(HYDROXYETHYL)ETHER Authors: Witzgall, F, Ewert, W, Blankenfeldt, W. Deposit date: 2017-07-07 Release date: 2017-09-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis. Chembiochem, 18, 2017

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