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3IVF
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BU of 3ivf by Molmil
Crystal structure of the talin head FERM domain
Descriptor: Talin-1
Authors:Elliott, P.R, Goult, B.T, Bate, N, Grossmann, J.G, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
Deposit date:2009-09-01
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The Structure of the talin head reveals a novel extended conformation of the FERM domain
Structure, 18, 2010
3G9W
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BU of 3g9w by Molmil
Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Integrin beta-1D, ...
Authors:Anthis, N.J, Wegener, K.L, Ye, F, Kim, C, Lowe, E.D, Vakonakis, I, Bate, N, Critchley, D.R, Ginsberg, M.H, Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
2RQ1
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BU of 2rq1 by Molmil
Solution structure of the 4.1R FERM alpha lobe domain
Descriptor: Protein 4.1
Authors:Kusunoki, H, Kohno, T.
Deposit date:2009-01-09
Release date:2009-04-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and glycophorin C binding studies of the protein 4.1R FERM alpha-lobe domain
Proteins, 76, 2009
2ZPY
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BU of 2zpy by Molmil
Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide
Descriptor: CD44 antigen, Radixin
Authors:Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T.
Deposit date:2008-07-31
Release date:2008-08-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for CD44 recognition by ERM proteins
J.Biol.Chem., 283, 2008
3BIN
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BU of 3bin by Molmil
Structure of the DAL-1 and TSLC1 (372-383) complex
Descriptor: Band 4.1-like protein 3, Cell adhesion molecule 1
Authors:Busam, R.D, Arrowsmith, C.H, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Berglund, H, Persson, C, Hallberg, B.M.
Deposit date:2007-11-30
Release date:2008-01-15
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B)
J.Biol.Chem., 286, 2011
2YVC
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BU of 2yvc by Molmil
Crystal structure of the Radixin FERM domain complexed with the NEP cytoplasmic tail
Descriptor: Neprilysin, Radixin
Authors:Terawaki, S, Kitano, K, Hakoshima, T.
Deposit date:2007-04-11
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex
J.Biol.Chem., 282, 2007
2YS3
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BU of 2ys3 by Molmil
Solution structure of the PH domain of Kindlin-3 from human
Descriptor: Unc-112-related protein 2
Authors:Li, H, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2007-10-09
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PH domain of Kindlin-3 from human
To be Published
2EMS
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BU of 2ems by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule CD43
Descriptor: Leukosialin, Radixin
Authors:Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-04-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
2EMT
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BU of 2emt by Molmil
Crystal Structure Analysis of the radixin FERM domain complexed with adhesion molecule PSGL-1
Descriptor: P-selectin glycoprotein ligand 1, Radixin
Authors:Takai, Y, Kitano, K, Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-03-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
2I1K
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Moesin from Spodoptera frugiperda reveals the coiled-coil domain at 3.0 angstrom resolution
Descriptor: CHLORIDE ION, GLYCEROL, Moesin, ...
Authors:Nance, M.R, Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2I1J
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Moesin from Spodoptera frugiperda at 2.1 angstroms resolution
Descriptor: CHLORIDE ION, GLYCEROL, Moesin, ...
Authors:Li, Q, Nance, M.R, Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2J0M
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Crystal structure a two-chain complex between the FERM and kinase domains of focal adhesion kinase.
Descriptor: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
Authors:Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
Deposit date:2006-08-03
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
2J0K
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
Descriptor: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
Authors:Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
Deposit date:2006-08-03
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for the Autoinhibition of Focal Adhesion Kinase.
Cell(Cambridge,Mass.), 129, 2007
2J0J
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Crystal structure of a fragment of focal adhesion kinase containing the FERM and kinase domains.
Descriptor: 1,2,3,4-TETRAHYDROGEN-STAUROSPORINE, FOCAL ADHESION KINASE 1
Authors:Lietha, D, Cai, X, Li, Y, Schaller, M.D, Eck, M.J.
Deposit date:2006-08-03
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for the Autoinhibition of Focal Adhesion Kinase
Cell(Cambridge,Mass.), 129, 2007
2HRJ
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BU of 2hrj by Molmil
NMR solution structure of the F2 subdomain of talin
Descriptor: Talin-1
Authors:Liu, G, Arroyo, M.M, Zheng, J.
Deposit date:2006-07-20
Release date:2008-04-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural characterization of the talin F2 FERM subdomain with Coenzyme A and PI(4,5)P2
To be Published
2HE7
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BU of 2he7 by Molmil
FERM domain of EPB41L3 (DAL-1)
Descriptor: Band 4.1-like protein 3
Authors:Hallberg, B.M, Busam, R.D, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Schiavone, L.H, Johansson, I, Hogbom, M, Karlberg, T, Kotenyova, T, Nilvebrandt, J, Norberg, P, Stenmark, P, Nordlund, P, Nilsson-ehle, P, Nyman, T, Ogg, D, Sagemark, J, Sundstrom, M, Uppenberg, J, Van den berg, S, Weigelt, J, Persson, C, Thorsell, A.G, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).
J.Biol.Chem., 286, 2011
2D2Q
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BU of 2d2q by Molmil
Crystal structure of the dimerized radixin FERM domain
Descriptor: Radixin
Authors:Kitano, K, Yusa, F, Hakoshima, T.
Deposit date:2005-09-15
Release date:2006-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2D11
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BU of 2d11 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-2 C-terminal tail peptide
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF2, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D10
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BU of 2d10 by Molmil
Crystal structure of the Radixin FERM domain complexed with the NHERF-1 C-terminal tail peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Radixin
Authors:Terawaki, S, Maesaki, R, Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2AL6
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BU of 2al6 by Molmil
FERM domain of Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-08-04
Release date:2005-10-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2AEH
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BU of 2aeh by Molmil
Focal adhesion kinase 1
Descriptor: Focal adhesion kinase 1
Authors:Ceccarelli, D.F, Song, H.K, Poy, F, Schaller, M.D, Eck, M.J.
Deposit date:2005-07-22
Release date:2005-10-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
1Y19
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BU of 1y19 by Molmil
Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M, Wegener, K, Santelli, E, Bate, N, Ginsberg, M.H, Critchley, D.R, Campbell, I.D, Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
1SGH
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BU of 1sgh by Molmil
Moesin FERM domain bound to EBP50 C-terminal peptide
Descriptor: Ezrin-radixin-moesin binding phosphoprotein 50, Moesin
Authors:Finnerty, C.M, Chambers, D, Ingraffea, J, Faber, H.R, Karplus, P.A, Bretscher, A.
Deposit date:2004-02-23
Release date:2004-06-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
1NI2
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BU of 1ni2 by Molmil
Structure of the active FERM domain of Ezrin
Descriptor: Ezrin
Authors:Smith, W.J, Nassar, N, Bretscher, A.P, Cerione, R.A, Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1J19
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Crystal structure of the radxin FERM domain complexed with the ICAM-2 cytoplasmic peptide
Descriptor: 16-mer peptide from Intercellular adhesion molecule-2, radixin
Authors:Hamada, K, Shimizu, T, Yonemura, S, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003

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