3U5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u5z by Molmil](/molmil-images/mine/3u5z) | Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
|
|
5FRQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5frq by Molmil](/molmil-images/mine/5frq) | |
1IQP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iqp by Molmil](/molmil-images/mine/1iqp) | Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RFCS | Authors: | Oyama, T, Ishino, Y, Cann, I.K.O, Ishino, S, Morikawa, K. | Deposit date: | 2001-07-24 | Release date: | 2001-09-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus Mol.Cell, 8, 2001
|
|
3U60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u60 by Molmil](/molmil-images/mine/3u60) | Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
|
|
4TSZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tsz by Molmil](/molmil-images/mine/4tsz) | Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa with ligand | Descriptor: | ACE-GLN-ALC-ASP-LEU-ZCL peptide, DNA polymerase III subunit beta | Authors: | Olieric, V, Burnouf, D, Ennifar, E, Wolff, P. | Deposit date: | 2014-06-19 | Release date: | 2014-09-10 | Last modified: | 2016-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins. J.Med.Chem., 57, 2014
|
|
8FS5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs5 by Molmil](/molmil-images/mine/8fs5) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 3 (open 9-1-1 and stably bound chamber DNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
8FS4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs4 by Molmil](/molmil-images/mine/8fs4) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2 (open 9-1-1 ring and flexibly bound chamber DNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
8FS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs8 by Molmil](/molmil-images/mine/8fs8) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1 encircling fully bound DNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
8FS3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs3 by Molmil](/molmil-images/mine/8fs3) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 1 (open 9-1-1 and shoulder bound DNA only) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
8FS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs6 by Molmil](/molmil-images/mine/8fs6) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4 (partially closed 9-1-1 and stably bound chamber DNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
8FS7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fs7 by Molmil](/molmil-images/mine/8fs7) | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5 (closed 9-1-1 and stably bound chamber DNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2023-01-09 | Release date: | 2023-06-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
|
|
7NF9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nf9 by Molmil](/molmil-images/mine/7nf9) | N-terminal C2H2 Zn-finger domain of Clamp | Descriptor: | Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION | Authors: | Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I. | Deposit date: | 2021-02-05 | Release date: | 2021-12-29 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila. Nucleic Acids Res., 50, 2022
|
|
4YS0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ys0 by Molmil](/molmil-images/mine/4ys0) | |
6PTH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pth by Molmil](/molmil-images/mine/6pth) | |
1UNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1unn by Molmil](/molmil-images/mine/1unn) | |
5G4Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g4q by Molmil](/molmil-images/mine/5g4q) | H.pylori Beta clamp in complex with 5-chloroisatin | Descriptor: | 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA | Authors: | Pandey, P, Gourinath, S. | Deposit date: | 2016-05-16 | Release date: | 2017-06-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
|
|
3RB9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rb9 by Molmil](/molmil-images/mine/3rb9) | |
4TR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tr7 by Molmil](/molmil-images/mine/4tr7) | |
4TR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tr8 by Molmil](/molmil-images/mine/4tr8) | Crystal structure of DNA polymerase sliding clamp from Pseudomonas aeruginosa | Descriptor: | DNA polymerase III subunit beta, SODIUM ION | Authors: | Olieric, V, Burnouf, D, Ennifar, E, Wolff, P. | Deposit date: | 2014-06-15 | Release date: | 2014-09-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins. J.Med.Chem., 57, 2014
|
|
4TR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4tr6 by Molmil](/molmil-images/mine/4tr6) | Crystal structure of DNA polymerase sliding clamp from Bacillus subtilis | Descriptor: | DNA polymerase III subunit beta, SODIUM ION | Authors: | Burnouf, D, Olieric, V, Ennifar, E, Wolff, P. | Deposit date: | 2014-06-14 | Release date: | 2014-09-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins. J.Med.Chem., 57, 2014
|
|
1JR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jr3 by Molmil](/molmil-images/mine/1jr3) | Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III | Descriptor: | DNA polymerase III subunit gamma, DNA polymerase III, delta subunit, ... | Authors: | Jeruzalmi, D, O'Donnell, M, Kuriyan, J. | Deposit date: | 2001-08-10 | Release date: | 2001-09-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
|
|
5G48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g48 by Molmil](/molmil-images/mine/5g48) | H.pylori Beta clamp in complex with Diflunisal | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA | Authors: | Pandey, P, Gourinath, S. | Deposit date: | 2016-05-06 | Release date: | 2017-06-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
|
|
3F1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f1v by Molmil](/molmil-images/mine/3f1v) | E. coli Beta Sliding Clamp, 148-153 Ala Mutant | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA polymerase III subunit beta | Authors: | Cody, V. | Deposit date: | 2008-10-28 | Release date: | 2009-09-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Sliding clamp-DNA interactions are required for viability and contribute to DNA polymerase management in Escherichia coli. J.Mol.Biol., 387, 2009
|
|
1NJF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1njf by Molmil](/molmil-images/mine/1njf) | Nucleotide bound form of an isolated E. coli clamp loader gamma subunit | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. | Deposit date: | 2002-12-30 | Release date: | 2003-04-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
|
|
1NJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1njg by Molmil](/molmil-images/mine/1njg) | Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit | Descriptor: | DNA polymerase III subunit gamma, SULFATE ION, ZINC ION | Authors: | Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. | Deposit date: | 2002-12-30 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
|
|