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1FVT
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THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR
Descriptor: 4-[(2Z)-2-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazinyl]benzene-1-sulfonamide, CELL DIVISION PROTEIN KINASE 2
Authors:Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K.
Deposit date:2000-09-20
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
1FVU
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CRYSTAL STRUCTURE OF BOTROCETIN
Descriptor: BOTROCETIN ALPHA CHAIN, BOTROCETIN BETA CHAIN, MAGNESIUM ION
Authors:Sen, U, Vasudevan, S, Subbarao, G, McClintoc, R.A, Celikel, R, Ruggeri, Z.M, Varughese, K.I.
Deposit date:2000-09-20
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the von Willebrand factor modulator botrocetin.
Biochemistry, 40, 2001
1FVV
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THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR
Descriptor: 4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE, CYCLIN A, CYCLIN-DEPENDENT KINASE 2
Authors:Davis, S.T, Benson, B.G, Bramson, H.N, Chapman, D.E, Dickerson, S.H, Dold, K.M, Eberwein, D.J, Edelstein, M, Frye, S.V, Gampe Jr, R.T, Griffin, R.J, Harris, P.A, Hassell, A.M, Holmes, W.D, Hunter, R.N, Knick, V.B, Lackey, K, Lovejoy, B, Luzzio, M.J, Murray, D, Parker, P, Rocque, W.J, Shewchuk, L, Veal, J.M, Walker, D.H, Kuyper, L.K.
Deposit date:2000-09-20
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
Science, 291, 2001
1FVX
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CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57N OXIDIZED
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
Authors:Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R.
Deposit date:1996-12-12
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes.
Biochemistry, 36, 1997
1FVY
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SOLUTION STRUCTURE OF THE OSTEOGENIC 1-31 FRAGMENT OF THE HUMAN PARATHYROID HORMONE
Descriptor: PARATHYROID HORMONE
Authors:Chen, Z.
Deposit date:2000-09-20
Release date:2000-11-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone.
Biochemistry, 39, 2000
1FW0
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH KAINATE AT 2.0 A RESOLUTION
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR SUBUNIT 2
Authors:Armstrong, N, Gouaux, E.
Deposit date:2000-09-20
Release date:2000-11-15
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FW1
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Glutathione transferase zeta/maleylacetoacetate isomerase
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLUTATHIONE, GLUTATHIONE TRANSFERASE ZETA, ...
Authors:Polekhina, G, Board, P.G, Blackburn, A.C, Parker, M.W.
Deposit date:2000-09-20
Release date:2001-09-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity.
Biochemistry, 40, 2001
1FW2
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OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI
Descriptor: CALCIUM ION, OUTER MEMBRANE PHOSPHOLIPASE A
Authors:Snijder, H.J, Kingma, R.L, Kalk, K.H, Dekker, N, Egmond, M.R, Dijkstra, B.W.
Deposit date:2000-09-21
Release date:2001-06-01
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural investigations of calcium binding and its role in activity and activation of outer membrane phospholipase A from Escherichia coli.
J.Mol.Biol., 309, 2001
1FW3
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OUTER MEMBRANE PHOSPHOLIPASE A FROM ESCHERICHIA COLI
Descriptor: OUTER MEMBRANE PHOSPHOLIPASE A
Authors:Snijder, H.J, Kingma, R.L, Kalk, K.H, Dekker, N, Egmond, M.R, Dijkstra, B.W.
Deposit date:2000-09-21
Release date:2001-06-01
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural investigations of calcium binding and its role in activity and activation of outer membrane phospholipase A from Escherichia coli.
J.Mol.Biol., 309, 2001
1FW4
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CRYSTAL STRUCTURE OF E. COLI FRAGMENT TR2C FROM CALMODULIN TO 1.7 A RESOLUTION
Descriptor: CALCIUM ION, CALMODULIN
Authors:Olsson, L.-L, Sjolin, L.
Deposit date:2000-09-21
Release date:2001-05-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Escherichia coli fragment TR2C from calmodulin to 1.7 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
1FW5
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SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1
Descriptor: NONSTRUCTURAL PROTEIN NSP1
Authors:Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L.
Deposit date:2000-09-21
Release date:2001-09-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Membrane binding mechanism of an RNA virus-capping enzyme.
J.Biol.Chem., 275, 2001
1FW6
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CRYSTAL STRUCTURE OF A TAQ MUTS-DNA-ADP TERNARY COMPLEX
Descriptor: 5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Junop, M.S, Obmolova, G, Rausch, K, Hsieh, P, Yang, W.
Deposit date:2000-09-21
Release date:2001-02-19
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair.
Mol.Cell, 7, 2001
1FW7
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NMR STRUCTURE OF 15N-LABELED BARNASE
Descriptor: BARNASE
Authors:Reibarkh, M.Y, Vasilieva, L.I, Schulga, A.A, Kirpichnikov, M.P, Arseniev, A.S.
Deposit date:2000-09-22
Release date:2003-06-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Refined Solution Structure and Backbone Dynamics of 15N-labeled Barnase Studied by NMR.
To be Published
1FW8
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CIRCULARLY PERMUTED PHOSPHOGLYCERATE KINASE FROM YEAST: PGK P72
Descriptor: GLYCEROL, Phosphoglycerate kinase
Authors:Tougard, P, Bizebard, T, Ritco-Vonsovici, M, Minard, P, Desmadril, M.
Deposit date:2000-09-22
Release date:2001-03-22
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a circularly permuted phosphoglycerate kinase.
Acta Crystallogr.,Sect.D, 58, 2002
1FW9
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CHORISMATE LYASE WITH BOUND PRODUCT
Descriptor: CHORISMATE LYASE, P-HYDROXYBENZOIC ACID
Authors:Gallagher, D.T, Mayhew, M, Holden, M, Vilker, V, Howard, A.
Deposit date:2000-09-22
Release date:2001-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The crystal structure of chorismate lyase shows a new fold and a tightly retained product.
Proteins, 44, 2001
1FWA
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 7.5
Descriptor: CARBONATE ION, NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWB
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 6.5
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWC
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 8.5
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWD
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 9.4
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWE
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT WITH ACETOHYDROXAMIC ACID (AHA) BOUND
Descriptor: ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWF
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KLEBSIELLA AEROGENES UREASE, C319D VARIANT
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWG
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KLEBSIELLA AEROGENES UREASE, C319S VARIANT
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWH
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KLEBSIELLA AEROGENES UREASE, C319Y VARIANT
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
1FWI
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KLEBSIELLA AEROGENES UREASE, H134A VARIANT
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of the mononickel metallocenter in H134A mutant urease.
J.Biol.Chem., 271, 1996
1FWJ
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KLEBSIELLA AEROGENES UREASE, NATIVE
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997

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