2K20
 
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2JXO
 | | Structure of the second PDZ domain of NHERF-1 | | Descriptor: | Ezrin-radixin-moesin-binding phosphoprotein 50 | | Authors: | Cheng, H, Li, J, Dai, Z, Bu, Z, Roder, H. | | Deposit date: | 2007-11-27 | | Release date: | 2008-12-09 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Autoinhibitory Interactions between the PDZ2 and C-terminal Domains in the Scaffolding Protein NHERF1
Structure, 17, 2009
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2I0I
 | | X-ray crystal structure of Sap97 PDZ3 bound to the C-terminal peptide of HPV18 E6 | | Descriptor: | Disks large homolog 1, peptide E6 | | Authors: | Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M. | | Deposit date: | 2006-08-10 | | Release date: | 2007-02-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007
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2JIK
 | | Crystal structure of PDZ domain of Synaptojanin-2 binding protein | | Descriptor: | SYNAPTOJANIN-2 BINDING PROTEIN | | Authors: | Tickle, J, Phillips, C, Pike, A.C.W, Cooper, C, Salah, E, Elkins, J, Turnbull, A.P, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D. | | Deposit date: | 2007-06-28 | | Release date: | 2007-07-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
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2JIL
 | | Crystal structure of 2nd PDZ domain of glutamate receptor interacting protein-1 (GRIP1) | | Descriptor: | 1,2-ETHANEDIOL, GLUTAMATE RECEPTOR INTERACTING PROTEIN-1, THIOCYANATE ION | | Authors: | Tickle, J, Elkins, J, Pike, A.C.W, Cooper, C, Salah, E, Papagrigoriou, E, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D. | | Deposit date: | 2007-06-28 | | Release date: | 2007-07-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of 2Nd Pdz Domain of Glutamate Receptor Interacting Protein-1 (Grip1)
To be Published
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2JIN
 | | Crystal structure of PDZ domain of Synaptojanin-2 binding protein | | Descriptor: | SODIUM ION, SULFATE ION, SYNAPTOJANIN-2 BINDING PROTEIN | | Authors: | Tickle, J, Phillips, C, Pike, A.C.W, Cooper, C, Salah, E, Elkins, J, Turnbull, A.P, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Doyle, D. | | Deposit date: | 2007-06-28 | | Release date: | 2007-07-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structure of Pdz Domain of Synaptojanin-2 Binding Protein
To be Published
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2KG2
 | | Solution structure of a PDZ protein | | Descriptor: | Tax1-binding protein 3 | | Authors: | Durney, M.A, Birrane, G, Anklin, C, Soni, A, Ladias, J.A.A. | | Deposit date: | 2009-03-02 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the human Tax-interacting protein-1.
J.Biomol.Nmr, 45, 2009
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2I1N
 | | Crystal structure of the 1st PDZ domain of Human DLG3 | | Descriptor: | Discs, large homolog 3, SODIUM ION | | Authors: | Turnbull, A.P, Phillips, C, Bunkoczi, G, Debreczeni, J, Ugochukwu, E, Pike, A.C.W, Gorrec, F, Umeano, C, Elkins, J, Berridge, G, Savitsky, P, Gileadi, O, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-08-14 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2KA9
 | | Solution structure of PSD-95 PDZ12 complexed with cypin peptide | | Descriptor: | Disks large homolog 4, cypin peptide | | Authors: | Wang, W.N, Weng, J.W, Zhang, X, Liu, M.L, Zhang, M.J. | | Deposit date: | 2008-11-03 | | Release date: | 2009-06-23 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95
J.Am.Chem.Soc., 131, 2009
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2FN5
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2KOJ
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2KJD
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2KAW
 | | NMR structure of the mDvl1 PDZ domain in complex with its inhibitor | | Descriptor: | Segment polarity protein dishevelled homolog DVL-1, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid | | Authors: | Lee, H.J, Shao, Y, Wang, N.X, Shi, D.L, Zheng, J.J. | | Deposit date: | 2008-11-17 | | Release date: | 2009-09-15 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled.
Angew.Chem.Int.Ed.Engl., 48, 2009
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2H3M
 | | Crystal Structure of ZO-1 PDZ1 | | Descriptor: | SULFATE ION, Tight junction protein ZO-1 | | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | Deposit date: | 2006-05-22 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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2H2B
 | | Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTYL) | | Descriptor: | ACETIC ACID, Tight junction protein ZO-1 | | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | | Deposit date: | 2006-05-18 | | Release date: | 2006-06-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity.
J.Biol.Chem., 281, 2006
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2KBS
 | | Solution structure of harmonin PDZ2 in complex with the carboxyl tail peptide of cadherin23 | | Descriptor: | Harmonin, octameric peptide from Cadherin-23 | | Authors: | Pan, L, Yan, J, Wu, L, Zhang, M. | | Deposit date: | 2008-12-05 | | Release date: | 2009-03-31 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
Proc.Natl.Acad.Sci.USA, 106, 2009
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2KOM
 | | Solution structure of humar Par-3b PDZ2 (residues 451-549) | | Descriptor: | Partitioning defective 3 homolog | | Authors: | Volkman, B.F, Tyler, R.C, Peterson, F.C, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2009-09-24 | | Release date: | 2009-11-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Rapid, robotic, small-scale protein production for NMR screening and structure determination.
Protein Sci., 19, 2010
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2KPL
 | | MAGI-1 PDZ1 / E6CT | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Protein E6 | | Authors: | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | Deposit date: | 2009-10-16 | | Release date: | 2010-10-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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2KPK
 | | MAGI-1 PDZ1 | | Descriptor: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | | Authors: | Charbonnier, S, Nomine, Y, Ramirez, J, Luck, K, Stote, R.H, Trave, G, Kieffer, B, Atkinson, R.A. | | Deposit date: | 2009-10-16 | | Release date: | 2010-10-27 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The structural and dynamic response of MAGI-1 PDZ1 with non-canonical domain boundaries to binding of human papillomavirus (HPV) E6
J.Mol.Biol., 2011
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2HE2
 | | Crystal structure of the 3rd PDZ domain of human discs large homologue 2, DLG2 | | Descriptor: | Discs large homolog 2 | | Authors: | Turnbull, A.P, Phillips, C, Berridge, G, Savitsky, P, Smee, C.E.A, Papagrigoriou, E, Debreczeni, J, Gorrec, F, Elkins, J.M, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-21 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2HE4
 | | The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif | | Descriptor: | 1,2-ETHANEDIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF2 | | Authors: | Papagrigoriou, E, Elkins, J.M, Berridge, G, Gileady, O, Colebrook, S, Gileadi, C, Salah, E, Savitsky, P, Pantic, N, Gorrec, F, Bunkoczi, G, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-06-21 | | Release date: | 2006-07-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2GZV
 | | The cystal structure of the PDZ domain of human PICK1 | | Descriptor: | PRKCA-binding protein | | Authors: | Debreczeni, J.E, Elkins, J.M, Yang, X, Berridge, G, Bray, J, Colebrook, S, Smee, C, Savitsky, P, Gileadi, O, Turnbull, A, von Delft, F, Doyle, D.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-05-12 | | Release date: | 2006-07-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
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2KOH
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2KV8
 | | Solution structure ofRGS12 PDZ domain | | Descriptor: | Regulator of G-protein signaling 12 | | Authors: | Lu, G, Ji, P, Huang, H. | | Deposit date: | 2010-03-10 | | Release date: | 2011-03-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Determining the Molecular Basis for the pH-dependent
Interaction between the PDZ of Human RGS12 and MEK2
To be Published
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2L4S
 | | Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L | | Descriptor: | Tax1-binding protein 3 | | Authors: | Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S. | | Deposit date: | 2010-10-13 | | Release date: | 2011-04-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
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