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1K3A
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BU of 1k3a by Molmil
Structure of the Insulin-like Growth Factor 1 Receptor Kinase
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, insulin receptor substrate 1, insulin-like growth factor 1 receptor
Authors:Favelyukis, S, Till, J.H, Hubbard, S.R, Miller, W.T.
Deposit date:2001-10-02
Release date:2001-11-28
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.
Nat.Struct.Biol., 8, 2001
1J9T
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BU of 1j9t by Molmil
Crystal structure of nitrite soaked reduced H255N AFNIR
Descriptor: COPPER (II) ION, COPPER-CONTAINING NITRITE REDUCTASE, NITRITE ION
Authors:Boulanger, M.J, Murphy, M.E.
Deposit date:2001-05-28
Release date:2001-06-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Alternate substrate binding modes to two mutant (D98N and H255N) forms of nitrite reductase from Alcaligenes faecalis S-6: structural model of a transient catalytic intermediate
Biochemistry, 40, 2001
6UXE
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BU of 6uxe by Molmil
Structure of the human mitochondrial desulfurase complex Nfs1-ISCU2(M140I)-ISD11 with E.coli ACP1 at 1.57 A resolution showing flexibility of N terminal end of ISCU2
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ...
Authors:Boniecki, M.T, Cygler, M.
Deposit date:2019-11-07
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
1JAJ
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BU of 1jaj by Molmil
Solution Structure of DNA Polymerase X from the African Swine Fever Virus
Descriptor: DNA POLYMERASE BETA-LIKE PROTEIN
Authors:Maciejewski, M.W, Shin, R, Pan, B, Mullen, G.P.
Deposit date:2001-05-30
Release date:2001-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a viral DNA repair polymerase.
Nat.Struct.Biol., 8, 2001
6CCQ
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BU of 6ccq by Molmil
Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 2-(3-chlorophenethyl)-1H-benzo[d]imidazol-4-ol
Descriptor: 2-[2-(3-chlorophenyl)ethyl]-1H-benzimidazol-7-ol, Phosphopantetheine adenylyltransferase, SULFATE ION
Authors:Mamo, M, Appleton, B.A.
Deposit date:2018-02-07
Release date:2018-03-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria.
J. Med. Chem., 61, 2018
1JW9
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BU of 1jw9 by Molmil
Structure of the Native MoeB-MoaD Protein Complex
Descriptor: MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 1, ...
Authors:Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H.
Deposit date:2001-09-03
Release date:2001-11-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.
Nature, 414, 2001
1JWD
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BU of 1jwd by Molmil
Ca2+-induced Structural Changes in Calcyclin: High-resolution Solution Structure of Ca2+-bound Calcyclin.
Descriptor: Calcyclin
Authors:Maler, L, Sastry, M, Chazin, W.J.
Deposit date:2001-09-04
Release date:2002-03-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A structural basis for S100 protein specificity derived from comparative analysis of apo and Ca(2+)-calcyclin
J.Mol.Biol., 317, 2002
6CD3
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BU of 6cd3 by Molmil
Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase I142A from Cupriavidus metallidurans in complex with 3-HAA
Descriptor: 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION
Authors:Yang, Y, Liu, F, Liu, A.
Deposit date:2018-02-07
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.612 Å)
Cite:Adapting to oxygen: 3-Hydroxyanthrinilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities.
J. Biol. Chem., 293, 2018
6P4W
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BU of 6p4w by Molmil
XPB helicase in a complex with truncated Bax1 from Sulfurisphaera tokodaii at 2.96 Angstrom resolution
Descriptor: CHLORIDE ION, DNA-dependent ATPase XPBII, Endonuclease Bax1, ...
Authors:Fan, L, He, F, DuPrez, K.T.
Deposit date:2019-05-28
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:XPB helicase in a complex with truncated Bax1 from Sulfurisphaera tokodaii at 2.96 Angstrom resolution
To Be Published
1JXS
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BU of 1jxs by Molmil
Solution Structure of the DNA-Binding Domain of Interleukin Enhancer Binding Factor
Descriptor: interleukin enhancer binding factor
Authors:Chuang, W.J, Liu, P.P, Li, C, Hsieh, Y.H, Chen, S.W, Chen, S.H, Jeng, W.Y.
Deposit date:2001-09-08
Release date:2003-03-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)
PROTEINS: STRUCT.,FUNCT.,GENET., 49, 2002
1JCR
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BU of 1jcr by Molmil
CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE
Descriptor: ACETIC ACID, FARNESYL DIPHOSPHATE, PROTEIN FARNESYLTRANSFERASE, ...
Authors:Long, S.B, Casey, P.J, Beese, L.S.
Deposit date:2001-06-11
Release date:2001-11-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JD8
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Solution structure of lactam analogue DapD of HIV gp41 600-612 loop
Descriptor: Transmembrane protein gp41
Authors:Phan Chan Du, A, Limal, D, Semetey, V, Dali, H, Jolivet, M, Desgranges, C, Cung, M.T, Briand, J.P, Petit, M.C, Muller, S.
Deposit date:2001-06-13
Release date:2003-07-01
Last modified:2025-03-26
Method:SOLUTION NMR
Cite:Structural and immunological characterisation of heteroclitic peptide analogues corresponding to the 600-612 region of the HIV envelope gp41 glycoprotein.
J.Mol.Biol., 323, 2002
6CD8
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BU of 6cd8 by Molmil
Complex of GID4 fragment with short peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide PSRV, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
4D0T
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BU of 4d0t by Molmil
GalNAc-T2 crystal soaked with UDP-GalNAc, EA2 peptide and manganese
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, MANGANESE (II) ION, ...
Authors:Lira-Navarrete, E, Iglesias-Fernandez, J, Zandberg, W.F, Companon, I, Kong, Y, Corzana, F, Pinto, B.M, Clausen, H, Peregrina, J.M, Vocadlo, D, Rovira, C, Hurtado-Guerrero, R.
Deposit date:2014-04-30
Release date:2014-05-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N-Acetylgalactosaminyltransferase 2.
Angew.Chem.Int.Ed.Engl., 53, 2014
6CDC
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BU of 6cdc by Molmil
GID4 in complex with a tetrapeptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide PGLW, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
1JDI
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BU of 1jdi by Molmil
CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE
Descriptor: L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION
Authors:Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Tanner, M.E, Strynadka, N.C.J.
Deposit date:2001-06-13
Release date:2002-01-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization.
Biochemistry, 40, 2001
6P5H
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BU of 6p5h by Molmil
Structure of MavC middle insertion domain
Descriptor: MavC
Authors:Negron Teron, K.I, Puvar, K, Iyer, S, Das, C.
Deposit date:2019-05-30
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
1JZB
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BU of 1jzb by Molmil
Crystal Structure of Variant 2 Scorpion Toxin from Centruroides sculpturatus Ewing
Descriptor: NEUROTOXIN 2
Authors:Cook, W.J, Zell, A, Watt, D.D, Ealick, S.E.
Deposit date:2001-09-14
Release date:2002-02-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure of variant 2 scorpion toxin from Centruroides sculpturatus Ewing.
Protein Sci., 11, 2002
8UKX
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BU of 8ukx by Molmil
Crystal structure the extracellular region of the epidermal growth factor receptor variant III (EGFRvIII) at pH 7.0
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Stayrook, S.E, Ferguson, K.M.
Deposit date:2023-10-15
Release date:2024-06-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structural insights into the role and targeting of EGFRvIII.
Structure, 32, 2024
1JZD
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BU of 1jzd by Molmil
DsbC-DsbDalpha complex
Descriptor: thiol:disulfide interchange protein dsbc, thiol:disulfide interchange protein dsbd
Authors:Haebel, P.W, Goldstone, D, Katzen, F, Beckwith, J, Metcalf, P.
Deposit date:2001-09-15
Release date:2003-03-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Disulfide Bond Isomerase DsbC is Activated by an Immunoglobulin-fold Thiol Oxidoreductase: Crystal structure of the DsbC-DsbDalpha complex.
Embo J., 21, 2002
6CDN
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BU of 6cdn by Molmil
Crystal structure of cysteine-bound ferrous form of the crosslinked Cl-Tyr157 human cysteine dioxygenase
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION, ...
Authors:Liu, A, Li, J, Shin, I.
Deposit date:2018-02-08
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Cleavage of a carbon-fluorine bond by an engineered cysteine dioxygenase.
Nat. Chem. Biol., 14, 2018
6P5O
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BU of 6p5o by Molmil
The structure of rat cytosolic PEPCK in complex with 3-(carboxymethylthiol)-picolinic acid
Descriptor: 3-[(carboxymethyl)sulfanyl]pyridine-2-carboxylic acid, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ...
Authors:Mcleod, M.J, Holyoak, T.
Deposit date:2019-05-30
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase.
Biochemistry, 58, 2019
4D61
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BU of 4d61 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
1JZK
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BU of 1jzk by Molmil
Crystal Structure of Scapharca inaequivalvis HbI, I114F mutant (deoxy)
Descriptor: GLOBIN I - ARK SHELL, PROTOPORPHYRIN IX CONTAINING FE
Authors:Knapp, J.E, Gibson, Q.H, Cushing, L, Royer Jr, W.E.
Deposit date:2001-09-16
Release date:2001-12-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Restricting the Ligand-Linked Heme Movement in Scapharca Dimeric Hemoglobin Reveals Tight Coupling between Distal and Proximal Contributions to Cooperativity.
Biochemistry, 40, 2001
8UIR
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BU of 8uir by Molmil
SARS-CoV-2 Omicron-XBB.1.16 3-RBD down Spike Protein Trimer consensus (S-GSAS-Omicron-XBB.1.16)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, Q.E, Acharya, P.
Deposit date:2023-10-10
Release date:2024-06-12
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Mol.Cell, 84, 2024

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