5THF
 
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9DIO
 | | Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/Texas/37/2024 (H5N1) with LSTc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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9DIP
 | | Crystal structure of H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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9DIQ
 | | Crystal structure of Apo-H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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5TH0
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5THC
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9DWE
 | | Cryo-EM structure of hemagglutinin H5 A/Texas/37/2024 in complex with LSTa and antibody CR9114 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab Fab heavy chain, CR9114 Fab light chain, ... | | Authors: | Fernandez-Quintero, M.L, Han, J, Rodriguez, A.J, Ward, A.B. | | Deposit date: | 2024-10-09 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-15 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth.
Nat Commun, 15, 2024
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8WH7
 | | apo toad HA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Zhang, D, Xie, Y.F, Chai, Y, Shi, Y, Liu, W.J, Qi, J.X, Gao, G.F, Gao, F. | | Deposit date: | 2023-09-22 | | Release date: | 2025-03-26 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Structural basis of receptor-binding adaptation of human-infecting H3N8 influenza A virus.
J.Virol., 99, 2025
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8UZC
 | | Structure of UT14 Fab in complex with the head domain of H3 (A/Singapore/INFIMH-16-0019/2016) | | Descriptor: | Hemagglutinin, UT14 Fab heavy chain, UT14 Fab light chain | | Authors: | Park, J, Georgiou, G. | | Deposit date: | 2023-11-14 | | Release date: | 2024-11-27 | | Last modified: | 2025-03-05 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Molecular features of the serological IgG repertoire elicited by egg-based, cell-based, or recombinant haemagglutinin-based seasonal influenza vaccines: a comparative, prospective, observational cohort study.
Lancet Microbe, 6, 2025
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5TGO
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9DM0
 | | Cryo-EM structure of the SFV009 3G01 Fab in complex with A/California/04/2009 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ... | | Authors: | Fernandez Quintero, M.L, Ferguson, J.A, Han, J, Ward, A.B. | | Deposit date: | 2024-09-11 | | Release date: | 2025-02-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of V H 3 and V K 3 genes.
Nat Commun, 16, 2025
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5THB
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8V7O
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5TG9
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9DS1
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5T0E
 | | Crystal structure of H6 hemagglutinin G225D mutant from Taiwan (2013) H6N1 influenza virus in complex with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, Hemagglutinin HA2 chain, ... | | Authors: | Wilson, I.A, Tzarum, N, Zhu, X. | | Deposit date: | 2016-08-15 | | Release date: | 2017-06-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human-type receptors.
EMBO Mol Med, 9, 2017
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9DRU
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5T08
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8VED
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8VEE
 | | Cryo-EM structure of antibody T5-1E08 in complex with H7N9 Influenza Hemagglutinin Trimer (A/Shanghai/2/13) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | Authors: | Cerutti, G, Casner, R.G, Shapiro, L. | | Deposit date: | 2023-12-18 | | Release date: | 2025-03-19 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Distinct binding modes drive the broad neutralization profile of two persistent influenza hemagglutinin stem-specific antibody lineages.
Structure, 33, 2025
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8VEB
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8VEF
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9BTO
 | | Influenza hemagglutinin B/Maryland/2016 glycoprotein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Torrents de la Pena, A, Sewall, L.M, Ward, A.B. | | Deposit date: | 2024-05-15 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Rapid and High-Throughput Imaging of Immune Complexes Using Microfluidics and Single Particle Electron Microscopy
Nat Biomed Eng, 2025
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8VUE
 | | L5A7 Fab bound to Indonesia2005 Hemagglutinin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | | Authors: | Olia, A.S, Gorman, J, Kwong, P.D. | | Deposit date: | 2024-01-29 | | Release date: | 2024-05-22 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody.
Front Immunol, 15, 2024
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9DS2
 | | Crystal structure of 346-54 Fab in complex with H1 HA from A/California/04/2009(H1N1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 346-54, ... | | Authors: | Lin, T.H, Wilson, I.A. | | Deposit date: | 2024-09-26 | | Release date: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (3.29 Å) | | Cite: | Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of V H 3 and V K 3 genes.
Nat Commun, 16, 2025
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