6ZLZ
 
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6ZML
 | | CryoEM Structure of Merkel Cell Polyomavirus Virus-like Particle | | Descriptor: | Capsid protein VP1 | | Authors: | Bayer, N.J, Januliene, D, Stehle, T, Moeller, A, Blaum, B.S. | | Deposit date: | 2020-07-03 | | Release date: | 2020-08-05 | | Last modified: | 2020-10-07 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of Merkel Cell Polyomavirus Capsid and Interaction with Its Glycosaminoglycan Attachment Receptor.
J.Virol., 94, 2020
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7B6T
 | | Sheep Polyomavirus VP1 in complex with 10 mM globo-N-tetraose | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose, ... | | Authors: | Rustmeier, N.H, Stehle, T. | | Deposit date: | 2020-12-08 | | Release date: | 2022-09-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.701 Å) | | Cite: | A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Biorxiv, 2023
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7B6V
 | | Sheep Polyomavirus VP1 in complex with 5 mM Forssman antigen pentaose and 20 mM 3'-sialyllactosamine | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | | Authors: | Rustmeier, N.H, Stehle, T. | | Deposit date: | 2020-12-08 | | Release date: | 2022-09-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Biorxiv, 2023
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7B6U
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7B6S
 | | Sheep Polyomavirus VP1 in complex with 10 mM Forssman antigen pentaose | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | | Authors: | Rustmeier, N.H, Stehle, T. | | Deposit date: | 2020-12-08 | | Release date: | 2022-09-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.923 Å) | | Cite: | A novel and highly specific Forssman antigen-binding protein from sheep polyomavirus
Biorxiv, 2023
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7B69
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7B6A
 | | BK Polyomavirus VP1 pentamer core (residues 30-299) | | Descriptor: | CALCIUM ION, DIMETHYL SULFOXIDE, IODIDE ION, ... | | Authors: | Osipov, E.M, Munawar, A, Beelen, S, Strelkov, S.V. | | Deposit date: | 2020-12-07 | | Release date: | 2022-06-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.
Rsc Chem Biol, 3, 2022
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4MBZ
 | | Structure of B-Lymphotropic Polyomavirus VP1 in complex with 3'-sialyllactosamine | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Khan, Z.M, Neu, U, Stehle, T. | | Deposit date: | 2013-08-21 | | Release date: | 2013-12-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands.
Plos Pathog., 9, 2013
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4JCF
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4MBX
 | | Structure of unliganded B-Lymphotropic Polyomavirus VP1 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Major Capsid Protein VP1 | | Authors: | Khan, Z.M, Neu, U, Schuch, B, Stehle, T. | | Deposit date: | 2013-08-21 | | Release date: | 2013-12-04 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands.
Plos Pathog., 9, 2013
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4MBY
 | | Structure of B-Lymphotropic Polyomavirus VP1 in complex with 3'-sialyllactose | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Khan, Z.M, Neu, U, Stehle, T. | | Deposit date: | 2013-08-21 | | Release date: | 2013-12-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Structures of B-Lymphotropic Polyomavirus VP1 in Complex with Oligosaccharide Ligands.
Plos Pathog., 9, 2013
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4MJ0
 | | BK Polyomavirus VP1 pentamer in complex with GD3 oligosaccharide | | Descriptor: | CHLORIDE ION, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, ... | | Authors: | Neu, U, Stroh, L.J, Stehle, T. | | Deposit date: | 2013-09-03 | | Release date: | 2013-11-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus.
Plos Pathog., 9, 2013
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4MJ1
 | | unliganded BK Polyomavirus VP1 pentamer | | Descriptor: | CHLORIDE ION, GLYCEROL, VP1 capsid protein | | Authors: | Neu, U, Stroh, L.J, Stehle, T. | | Deposit date: | 2013-09-03 | | Release date: | 2013-11-06 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus.
Plos Pathog., 9, 2013
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7ZIO
 | | JC Polyomavirus VP1 in complex with 6'-Sialyllactose glycomacromolecules (aromatic linker) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Freytag, J, Mueller, J.C, Stehle, T. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022
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7ZIM
 | | JC Polyomavirus VP1 in complex with 3'-Sialyllactose glycomacromolecules (aromatic linker) | | Descriptor: | DI(HYDROXYETHYL)ETHER, Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, ... | | Authors: | Freytag, J, Mueller, J.C, Stehle, T. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022
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7ZIQ
 | | BK Polyomavirus VP1 in complex with 6'-Sialyllactose glycomacromolecules (aromatic linker) | | Descriptor: | 1,2-ETHANEDIOL, Capsid protein VP1, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Freytag, J, Mueller, J.C, Stehle, T. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022
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7ZIL
 | | JC Polyomavirus VP1 in complex with 3'-Sialyllactose glycomacromolecules (aliphatic linker) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Freytag, J, Mueller, J.C, Stehle, T. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022
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7ZIN
 | | JC Polyomavirus VP1 in complex with 6'-Sialyllactose glycomacromolecules (aliphatic linker) | | Descriptor: | 1,2-ETHANEDIOL, Major capsid protein VP1, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, ... | | Authors: | Freytag, J, Mueller, J.C, Stehle, T. | | Deposit date: | 2022-04-08 | | Release date: | 2022-12-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.648 Å) | | Cite: | Synthesis of Homo- and Heteromultivalent Fucosylated and Sialylated Oligosaccharide Conjugates via Preactivated N -Methyloxyamine Precision Macromolecules and Their Binding to Polyomavirus Capsid Proteins.
Biomacromolecules, 23, 2022
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7ZIP
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8AH0
 | | BK Polyomavirus VP1 mutant VQQ | | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | Authors: | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AH1
 | | BK Polyomavirus VP1 mutant N-Q | | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | Authors: | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.006 Å) | | Cite: | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AGO
 | | BK Polyomavirus VP1 mutant E73Q | | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | Authors: | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.853 Å) | | Cite: | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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8AGH
 | | BK Polyomavirus VP1 mutant E73A | | Descriptor: | CHLORIDE ION, GLYCEROL, Major capsid protein VP1 | | Authors: | Sorin, M.N, Di Maio, A, Silva, L.M, Ebert, D, Delannoy, C, Nguyen, N.-K, Guerardel, Y, Chai, W, Halary, F, Renaudin-Autain, K, Liu, Y, Bressollette-Bodin, C, Stehle, T, McIlroy, D. | | Deposit date: | 2022-07-20 | | Release date: | 2023-02-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.887 Å) | | Cite: | Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus.
Cell Rep, 42, 2023
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4WDZ
 | | JC Polyomavirus VP1 five-fold pore mutant N221W | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1 | | Authors: | Stroh, L.J, Stehle, T. | | Deposit date: | 2014-09-09 | | Release date: | 2015-02-18 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins.
J.Virol., 89, 2015
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