9ICI
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9ICP
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1ZQH
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1ZQG
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1MQ2
| Human DNA Polymerase Beta Complexed With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine and dAMP | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(2DA))-3', ... | Authors: | Krahn, J.M, Beard, W.A, Miller, H, Grollman, A.P, Wilson, S.H. | Deposit date: | 2002-09-13 | Release date: | 2003-01-28 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of DNA Polymerase beta with the Mutagenic DNA Lesion 8-oxodeoxyguanine Reveals
Structural Insights into its Coding Potential Structure, 11, 2003
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7ICL
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7ICF
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8ICY
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8ICB
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8ICL
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8ICT
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8ICZ
| DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF OF DATP (1 MILLIMOLAR), MNCL2 (5 MILLIMOLAR), AND LITHIUM SULFATE (75 MILLIMOLAR) | Descriptor: | DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... | Authors: | Pelletier, H, Sawaya, M.R. | Deposit date: | 1996-01-04 | Release date: | 1996-11-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
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6U6B
| Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... | Authors: | Ouzon-Shubeita, H, Vilas, C.K, Lee, S. | Deposit date: | 2019-08-29 | Release date: | 2020-09-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.108 Å) | Cite: | Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion. Biochem.J., 477, 2020
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9ICB
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1ZQC
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1ZQO
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1ZQB
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1ZQM
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1ZQA
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1ZQK
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8ICJ
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8ICV
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8ICE
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9ICE
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1ZQL
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