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PDB: 764 results

7SJ6
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BU of 7sj6 by Molmil
T4 Lysozyme L99A/M102H with 1,2-Azaborine bound
Descriptor: 1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, ACETATE ION, ...
Authors:Yao, L, Wirth, J.
Deposit date:2021-10-16
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:T4 Lysozyme L99A/M102H with 1,2-Azaborine bound
to be published
4I7O
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BU of 4i7o by Molmil
T4 Lysozyme L99A/M102H with 2-amino-5-chlorothiazole bound
Descriptor: 2-HYDROXYETHYL DISULFIDE, 5-chloro-1,3-thiazol-2-amine, ACETATE ION, ...
Authors:Merski, M, Shoichet, B.K.
Deposit date:2012-11-30
Release date:2013-03-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The impact of introducing a histidine into an apolar cavity site on docking and ligand recognition.
J.Med.Chem., 56, 2013
3CDV
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BU of 3cdv by Molmil
Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:Mooers, B.H.M.
Deposit date:2008-02-27
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009
232L
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BU of 232l by Molmil
T4 LYSOZYME MUTANT M120K
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W.
Deposit date:1997-10-05
Release date:1998-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Protein Sci., 7, 1998
5JGV
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BU of 5jgv by Molmil
Spin-Labeled T4 Lysozyme Construct A73V1
Descriptor: CHLORIDE ION, Endolysin, HEXANE-1,6-DIOL, ...
Authors:Balo, A.R, Feyrer, H, Ernst, O.P.
Deposit date:2016-04-20
Release date:2017-02-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.732 Å)
Cite:Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.
Biochemistry, 55, 2016
102L
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BU of 102l by Molmil
HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Heinz, D.W, Matthews, B.W.
Deposit date:1992-09-29
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme.
Nature, 361, 1993
4EPI
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BU of 4epi by Molmil
The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds
Descriptor: Pesticin, Lysozyme Chimera, SODIUM ION, ...
Authors:Seddiki, N, Fairman, J.W, Noinaj, N, Lukacik, P, Barnard, T, Buchanan, S.K.
Deposit date:2012-04-17
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural engineering of a phage lysin that targets Gram-negative pathogens.
Proc.Natl.Acad.Sci.USA, 109, 2012
5I14
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BU of 5i14 by Molmil
Truncated and mutated T4 lysozyme
Descriptor: NICKEL (II) ION, mutated and truncated T4 lysozyme
Authors:Klima, M, Boura, E.
Deposit date:2016-02-05
Release date:2016-02-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.745 Å)
Cite:Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography.
Protein Sci., 26, 2017
1L90
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BU of 1l90 by Molmil
SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1992-01-21
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences.
J.Mol.Biol., 229, 1993
165L
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BU of 165l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
1QUD
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BU of 1qud by Molmil
L99G MUTANT OF T4 LYSOZYME
Descriptor: CHLORIDE ION, HEXANE-1,6-DIOL, PROTEIN (LYSOZYME)
Authors:Wray, J, Baase, W.A, Lindstrom, J.D, Poteete, A.R, Matthews, B.W.
Deposit date:1999-07-01
Release date:1999-07-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability.
J.Mol.Biol., 292, 1999
1DYB
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BU of 1dyb by Molmil
DETERMINATION OF ALPHA-HELIX PROPENSITY WITHIN THE CONTEXT OF A FOLDED PROTEIN: SITES 44 AND 131 IN BACTERIOPHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Zhang, X, Matthews, B.W.
Deposit date:1993-05-13
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
J.Mol.Biol., 235, 1994
243L
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BU of 243l by Molmil
THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
Authors:Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
Deposit date:1997-10-22
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
180L
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BU of 180l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: LYSOZYME
Authors:Kuroki, R, Weaver, L, Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
1L59
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BU of 1l59 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
1L41
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BU of 1l41 by Molmil
CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
Descriptor: T4 LYSOZYME
Authors:Daopin, S, Matthews, B.W.
Deposit date:1991-01-28
Release date:1991-10-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis.
Biochemistry, 30, 1991
1L63
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BU of 1l63 by Molmil
ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Nicholson, H, Matthews, B.W.
Deposit date:1991-05-06
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry, 30, 1991
240L
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BU of 240l by Molmil
THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
Authors:Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
Deposit date:1997-10-22
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
206L
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BU of 206l by Molmil
PHAGE T4 LYSOZYME
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1996-03-19
Release date:1996-08-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993
166L
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BU of 166l by Molmil
CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
Authors:Blaber, M, Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
1KW5
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BU of 1kw5 by Molmil
METHIONINE CORE MUTANT OF T4 LYSOZYME
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
Authors:Gassner, N.C, Baase, W.A, Mooers, B.H, Busam, R.D, Weaver, L.H, Lindstrom, J.D, Quillin, M.L, Matthews, B.W.
Deposit date:2002-01-28
Release date:2003-06-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability
BIOPHYS.CHEM., 100, 2003
247L
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BU of 247l by Molmil
THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME
Authors:Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W.
Deposit date:1997-10-23
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein Sci., 7, 1998
2CUU
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BU of 2cuu by Molmil
Crystal structure of spin labeled T4 Lysozyme (V131R1)
Descriptor: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
Authors:Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
Deposit date:2005-05-28
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
212L
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BU of 212l by Molmil
PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME
Descriptor: 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME
Authors:Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W.
Deposit date:1996-09-23
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme.
Protein Sci., 5, 1996
3C7W
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BU of 3c7w by Molmil
Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
Authors:Mooers, B.H.M.
Deposit date:2008-02-08
Release date:2009-02-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein Sci., 18, 2009

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