1B2M
| THREE-DIMENSIONAL STRUCTURE OF RIBONULCEASE T1 COMPLEXED WITH AN ISOSTERIC PHOSPHONATE ANALOGUE OF GPU: ALTERNATE SUBSTRATE BINDING MODES AND CATALYSIS. | Descriptor: | 5'-R(*GP*(U34))-3', RIBONUCLEASE T1 | Authors: | Arni, R.K, Watanabe, L, Ward, R.J, Kreitman, R.J, Kumar, K, Walz Jr, F.G. | Deposit date: | 1998-11-27 | Release date: | 1999-03-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis. Biochemistry, 38, 1999
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7GSP
| RIBONUCLEASE T1/2',3'-CGPS, NON-PRODUCTIVE | Descriptor: | GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, PHOSPHATE ION, RIBONUCLEASE T1 | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1997-12-10 | Release date: | 1998-03-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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1FYS
| Ribonuclease T1 V16C mutant | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | Authors: | De Vos, S, Loris, R, Steyaert, J. | Deposit date: | 2000-10-03 | Release date: | 2000-10-25 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Hydrophobic core manipulations in ribonuclease T1. Biochemistry, 40, 2001
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1RGL
| RNASE T1 MUTANT GLU46GLN BINDS THE INHIBITORS 2'GMP AND 2'AMP AT THE 3' SUBSITE | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 | Authors: | Granzin, J, Puras-Lutzke, R, Landt, O, Grunert, H.-P, Heinemann, U, Saenger, W, Hahn, U. | Deposit date: | 1992-02-19 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | RNase T1 mutant Glu46Gln binds the inhibitors 2'GMP and 2'AMP at the 3' subsite. J.Mol.Biol., 225, 1992
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1RGC
| THE COMPLEX BETWEEN RIBONUCLEASE T1 AND 3'-GUANYLIC ACID SUGGESTS GEOMETRY OF ENZYMATIC REACTION PATH. AN X-RAY STUDY | Descriptor: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | Authors: | Heydenreich, A, Koellner, G, Choe, H.W, Cordes, F, Kisker, C, Schindelin, H, Adamiak, R, Hahn, U, Saenger, W. | Deposit date: | 1993-05-12 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The complex between ribonuclease T1 and 3'GMP suggests geometry of enzymic reaction path. An X-ray study. Eur.J.Biochem., 218, 1993
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4HOH
| RIBONUCLEASE T1 (THR93ALA MUTANT) COMPLEXED WITH 2'GMP | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | Authors: | Langhorst, U, Loris, R, Denisov, V.P, Doumen, J, Roose, P, Maes, D, Halle, B, Steyaert, J. | Deposit date: | 1998-09-14 | Release date: | 1998-09-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1. Protein Sci., 8, 1999
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1TTO
| Crystal structure of the Rnase T1 variant R2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RNase T1 | Authors: | Hahn, U, Czaja, R, Perbandt, M, Betzel, C. | Deposit date: | 2004-06-23 | Release date: | 2005-09-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Purine activity of RNase T1RV is further improved by substitution of Trp59 by tyrosine Biochem.Biophys.Res.Commun., 336, 2005
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6GSP
| RIBONUCLEASE T1/3'-GMP, 15 WEEKS | Descriptor: | CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1 | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1997-12-09 | Release date: | 1998-03-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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1GSP
| RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY | Descriptor: | CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, RIBONUCLEASE T1 | Authors: | Zegers, I, Wyns, L. | Deposit date: | 1997-11-28 | Release date: | 1998-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography. Nat.Struct.Biol., 5, 1998
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4RNT
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1TRQ
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1CH0
| RNASE T1 VARIANT WITH ALTERED GUANINE BINDING SEGMENT | Descriptor: | CALCIUM ION, CHLORIDE ION, GUANOSINE-2'-MONOPHOSPHATE, ... | Authors: | Hoeschler, K, Hoier, H, Orth, P, Hubner, B, Saenger, W, Hahn, U. | Deposit date: | 1999-03-30 | Release date: | 1999-12-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of an RNase T1 variant with an altered guanine binding segment. J.Mol.Biol., 294, 1999
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2BIR
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1I3F
| Ribonuclease T1 V89S mutant | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1 | Authors: | De Vos, S, Backmann, J, Steyaert, J, Loris, R. | Deposit date: | 2001-02-15 | Release date: | 2001-03-07 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Hydrophobic core manipulations in ribonuclease T1 Biochemistry, 40, 2001
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1TRP
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3URP
| Re-refinement of PDB entry 5RNT - ribonuclease T1 with guanosine-3',5'-diphosphate and phosphate ion bound | Descriptor: | GUANOSINE-3',5'-DIPHOSPHATE, Guanyl-specific ribonuclease T1, PHOSPHATE ION, ... | Authors: | Smart, O.S, Womack, T.O, Flensburg, C, Keller, P, Sharff, A, Paciorek, W, Vonrhein, C, Bricogne, G. | Deposit date: | 2011-11-22 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER. Acta Crystallogr.,Sect.D, 68, 2012
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5RNT
| X-RAY ANALYSIS OF CUBIC CRYSTALS OF THE COMPLEX FORMED BETWEEN RIBONUCLEASE T1 AND GUANOSINE-3',5'-BISPHOSPHATE | Descriptor: | GUANOSINE-3',5'-DIPHOSPHATE, RIBONUCLEASE T1 | Authors: | Saenger, W, Heinemann, U, Lenz, A. | Deposit date: | 1991-03-28 | Release date: | 1993-01-15 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | X-ray analysis of cubic crystals of the complex formed between ribonuclease T1 and guanosine-3',5'-bisphosphate. Acta Crystallogr.,Sect.B, 47, 1991
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1YGW
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1IYY
| NMR STRUCTURE OF Gln25-RIBONUCLEASE T1, 24 STRUCTURES | Descriptor: | RIBONUCLEASE T1 | Authors: | Hatano, K, Kojima, M, Suzuki, E, Tanokura, M, Takahashi, K. | Deposit date: | 2002-09-12 | Release date: | 2003-10-07 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Determination of the NMR structure of Gln25-ribonuclease T1. Biol. Chem., 384, 2003
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