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PDB: 65 results

3TT1
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BU of 3tt1 by Molmil
Crystal Structure of LeuT in the outward-open conformation in complex with Fab
Descriptor: Leucine transporter LeuT, SODIUM ION, mouse monoclonal 1gG2a Fab fragment, ...
Authors:Krishnamurthy, H, Gouaux, E.
Deposit date:2011-09-13
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.099 Å)
Cite:X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
4MM6
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BU of 4mm6 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (S)-duloxetine
Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
3USI
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BU of 3usi by Molmil
Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
4MM5
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BU of 4mm5 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with sertraline
Descriptor: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
3TT3
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BU of 3tt3 by Molmil
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
Descriptor: Leucine transporter LeuT, mouse monoclonal 1gG1 Fab fragment, heavy chain, ...
Authors:Krishnamurthy, H, Gouaux, E.
Deposit date:2011-09-13
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:X-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Nature, 481, 2012
4MMA
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BU of 4mma by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with clomipramine
Descriptor: 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
4HOD
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BU of 4hod by Molmil
Crystal structure of LeuT-E290S with bound Cl
Descriptor: CHLORIDE ION, LEUCINE, SODIUM ION, ...
Authors:Kantcheva, A.K, Quick, M, Shi, L, Winther, A.M.L, Stolzenberg, S, Weinstein, H, Javitch, J.A, Nissen, P.
Deposit date:2012-10-22
Release date:2013-05-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The chloride binding site of Neurotransmitter Sodium Symporters
Proc.Natl.Acad.Sci.USA, 2013
4MM8
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BU of 4mm8 by Molmil
Crystal structure of LeuBAT (delta13 mutant) in complex with (R)-fluoxetine
Descriptor: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, SODIUM ION, Transporter
Authors:Wang, H, Gouaux, E.
Deposit date:2013-09-08
Release date:2013-10-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structural basis for action by diverse antidepressants on biogenic amine transporters.
Nature, 503, 2013
7DIX
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BU of 7dix by Molmil
Crystal structure of LeuT in lipidic cubic phase at pH 5
Descriptor: Na(+):neurotransmitter symporter (Snf family), SELENOMETHIONINE, SODIUM ION
Authors:Fan, J, Xiao, Y, Sun, Z, Zhou, X.
Deposit date:2020-11-19
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
J.Biol.Chem., 296, 2021
3USJ
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BU of 3usj by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
7DJ1
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BU of 7dj1 by Molmil
Crystal structure of the G26C mutant of LeuT
Descriptor: LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION
Authors:Fan, J, Xiao, Y, Sun, Z, Zhou, X.
Deposit date:2020-11-19
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.528 Å)
Cite:Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
J.Biol.Chem., 296, 2021
8FT5
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BU of 8ft5 by Molmil
Crystal structure of LeuT soaked with Crown-5
Descriptor: CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ...
Authors:Karasawa, A, Liu, H, Quick, M, Hendrickson, A.H, Liu, Q.
Deposit date:2023-01-11
Release date:2023-11-22
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystallographic characterization of sodium ions in a bacterial leucine/sodium symporter
To be Published
8FT4
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BU of 8ft4 by Molmil
Multicrystal structure of Na+, leucine-bound LeuT determined at 5 keV
Descriptor: CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ...
Authors:Karasawa, A, Liu, H, Quick, M, Hendrickson, A.H, Liu, Q.
Deposit date:2023-01-11
Release date:2023-11-22
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystallographic characterization of sodium ions in a bacterial leucine/sodium symporter
To be Published
3USK
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BU of 3usk by Molmil
Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles
Descriptor: LEUCINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
3USO
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BU of 3uso by Molmil
Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles
Descriptor: SELENOMETHIONINE, SODIUM ION, Transporter
Authors:Wang, H, Elferich, J, Gouaux, E.
Deposit date:2011-11-23
Release date:2012-01-11
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
Nat.Struct.Mol.Biol., 19, 2012
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