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PDB: 114 results

3SGU
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Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase covalently modified by 5-fluoro-6-iodo-UMP
Descriptor: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase
Authors:Liu, Y, Kotra, L.P, Pai, E.F.
Deposit date:2011-06-15
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase covalently modified by 5-fluoro-6-iodo-UMP
To be Published
3SEC
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Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
Descriptor: (1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Liu, Y, Kotra, L.P, Pai, E.F.
Deposit date:2011-06-10
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of methanococcus thermolithotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
To be Published
4FXR
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Crystal structure of the mutant T159V.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase
Authors:Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C.
Deposit date:2012-07-03
Release date:2013-05-22
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.708 Å)
Cite:Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry, 51, 2012
3WJY
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Orotidine 5'-monophosphate decarboxylase K72A mutant from M. thermoautotrophicus complexed with 6-amino-UMP
Descriptor: 6-AMINOURIDINE 5'-MONOPHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F, Miki, K.
Deposit date:2013-10-17
Release date:2013-12-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase.
J.Am.Chem.Soc., 135, 2013
4NT0
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Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 3-deazauridine 5'-monophosphate
Descriptor: 4-hydroxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridin-2(1H)-one, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Fedorov, A.A, Fedorov, E.V, Iiams, V, Gerlt, J.A, Almo, S.C.
Deposit date:2013-11-29
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 3-deazauridine 5'-monophosphate
To be Published
1DV7
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CRYSTAL STRUCTURE OF OROTIDINE MONOPHOSPHATE DECARBOXYLASE
Descriptor: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Authors:Wu, N, Mo, Y, Gao, J, Pai, E.F.
Deposit date:2000-01-20
Release date:2000-04-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase.
Proc.Natl.Acad.Sci.USA, 97, 2000
2ZZ3
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Covalent complex of orotidine monophosphate decarboxylase D70A mutant from M. thermoautotrophicus with 6-cyano-UMP
Descriptor: 6-cyanouridine 5'-phosphate, GLYCEROL, Orotidine 5'-phosphate decarboxylase
Authors:Fujihashi, M, Pai, E.F.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the molecular events during a slow substrate-product transition in orotidine 5'-monophosphate decarboxylase
J.Mol.Biol., 387, 2009
1LOS
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crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP
Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, orotidine monophosphate decarboxylase
Authors:Wu, N, Pai, E.F.
Deposit date:2002-05-06
Release date:2002-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J.Biol.Chem., 277, 2002
1LP6
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Crystal structure of orotidine monophosphate decarboxylase complexed with CMP
Descriptor: CYTIDINE-5'-MONOPHOSPHATE, orotidine monophosphate decarboxylase
Authors:Wu, N, Pai, E.F.
Deposit date:2002-05-07
Release date:2002-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J.Biol.Chem., 277, 2002
1LOL
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Crystal structure of orotidine monophosphate decarboxylase complex with XMP
Descriptor: 1,3-BUTANEDIOL, XANTHOSINE-5'-MONOPHOSPHATE, orotidine 5'-monophosphate decarboxylase
Authors:Wu, N, Pai, E.F.
Deposit date:2002-05-06
Release date:2002-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J.Biol.Chem., 277, 2002
4FX8
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Crystal structure of the mutant Q185A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION
Authors:Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C.
Deposit date:2012-07-02
Release date:2013-06-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9411 Å)
Cite:Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry, 51, 2012
4O8R
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Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
Descriptor: 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, Orotidine 5'-phosphate decarboxylase
Authors:Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C.
Deposit date:2013-12-29
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
To be Published
3G1H
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Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
Descriptor: 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase
Authors:Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C.
Deposit date:2009-01-29
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.
Biochemistry, 48, 2009
3G1F
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Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydroorotidine 5'-monophosphate
Descriptor: 5,6-dihydroorotidine 5'-monophosphate, Orotidine 5'-phosphate decarboxylase
Authors:Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C.
Deposit date:2009-01-29
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.
Biochemistry, 48, 2009

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