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PDB: 177 件
1KEN
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INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION
分子名称: alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin HA1, hemagglutinin HA2, ...
著者Barbey-Martin, C, Gigant, B, Bizebard, T, Calder, L.J, Wharto, S.A, Skehel, J.J, Knossow, M.
登録日2001-11-16
公開日2002-04-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献An Antibody that Prevents the Hemagglutinin Low pH Fusogenic Transition
VIROLOGY, 294, 2002
1HGG
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BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ...
著者Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C.
登録日1991-11-01
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
Biochemistry, 31, 1992
1HGH
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BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
分子名称: 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ...
著者Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C.
登録日1991-11-01
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
Biochemistry, 31, 1992
1HGI
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BU of 1hgi by Molmil
BINDING OF INFLUENZA VIRUS HEMAGGLUTININ TO ANALOGS OF ITS CELL-SURFACE RECEPTOR, SIALIC ACID: ANALYSIS BY PROTON NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND X-RAY CRYSTALLOGRAPHY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, CHAIN HA1, ...
著者Sauter, N.K, Hanson, J.E, Glick, G.D, Brown, J.H, Crowther, R.L, Park, S.-J, Skehel, J.J, Wiley, D.C.
登録日1991-11-01
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
Biochemistry, 31, 1992
1EO8
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BU of 1eo8 by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ...
著者Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T.
登録日2000-03-22
公開日2000-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000
3CKZ
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N1 Neuraminidase H274Y + Zanamivir
分子名称: CALCIUM ION, Neuraminidase, ZANAMIVIR
著者Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL2
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N1 Neuraminidase N294S + Oseltamivir
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
著者Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.538 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL0
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N1 Neuraminidase H274Y + oseltamivir
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase
著者Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
1HTM
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BU of 1htm by Molmil
STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION
分子名称: HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN
著者Bullough, P.A, Hughson, F.M, Skehel, J.J, Wiley, D.C.
登録日1994-11-02
公開日1995-02-14
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of influenza haemagglutinin at the pH of membrane fusion.
Nature, 371, 1994
2HMG
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BU of 2hmg by Molmil
REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ (HA1 CHAIN), HEMAGGLUTININ (HA2 CHAIN), ...
著者Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C.
登録日1989-09-11
公開日1991-01-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
1QFU
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BU of 1qfu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ...
著者Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M.
登録日1999-04-14
公開日1999-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999
1MQM
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BHA/LSTa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者ha, y, steven, d.j, skehel, j.j, wiley, d.c.
登録日2002-09-16
公開日2003-08-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.
Virology, 309, 2003
1MQN
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BHA/LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者ha, y, stevens, d.j, skehel, j.j, wiley, d.c.
登録日2002-09-16
公開日2003-08-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.
Virology, 309, 2003
1MQL
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BU of 1mql by Molmil
BHA of Ukr/63
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者ha, y, stevens, d.j, skehel, j.j, wiley, d.c.
登録日2002-09-16
公開日2003-08-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus.
Virology, 309, 2003
5JW4
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BU of 5jw4 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H5 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
1EBO
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BU of 1ebo by Molmil
CRYSTAL STRUCTURE OF THE EBOLA VIRUS MEMBRANE-FUSION SUBUNIT, GP2, FROM THE ENVELOPE GLYCOPROTEIN ECTODOMAIN
分子名称: CHLORIDE ION, EBOLA VIRUS ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO A FRAGMENT OF GP2, ZINC ION
著者Weissenhorn, W, Carfi, A, Lee, K.H, Skehel, J.J, Wiley, D.C.
登録日1998-11-03
公開日1999-07-02
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.
Mol.Cell, 2, 1998
5JW3
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BU of 5jw3 by Molmil
Structure of MEDI8852 Fab Fragment in Complex with H7 HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW5
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BU of 5jw5 by Molmil
Structure of MEDI8852 Fab Fragment
分子名称: MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
著者Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J.
登録日2016-05-11
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
1ENV
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BU of 1env by Molmil
ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41
分子名称: HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41
著者Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C.
登録日1997-06-27
公開日1997-11-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Atomic structure of the ectodomain from HIV-1 gp41.
Nature, 387, 1997
1FAV
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BU of 1fav by Molmil
THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE
分子名称: HIV-1 ENVELOPE PROTEIN CHIMERA, PROTEIN (TRANSMEMBRANE GLYCOPROTEIN)
著者Zhou, G, Ferrer, M, Chopra, R, Strassmaier, T, Weissenhorn, W, Skehel, J.J, Oprian, D, Schreiber, S.L, Harrison, S.C, Wiley, D.C.
登録日2000-07-13
公開日2000-08-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.
Bioorg.Med.Chem., 8, 2000
1QU1
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BU of 1qu1 by Molmil
CRYSTAL STRUCTURE OF EHA2 (23-185)
分子名称: PROTEIN (INFLUENZA RECOMBINANT HA2 CHAIN)
著者Chen, J, Skehel, J.J, Wiley, D.C.
登録日1999-07-05
公開日2000-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
Proc.Natl.Acad.Sci.USA, 96, 1999
1RVX
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BU of 1rvx by Molmil
1934 H1 Hemagglutinin in complex with LSTA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S, Elliot, A, Wiley, D.C, Skehel, J.J.
登録日2003-12-15
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1RVZ
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1934 H1 Hemagglutinin in complex with LSTC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
著者Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S, Elliot, A, Wiley, D.C, Skehel, J.J.
登録日2003-12-15
公開日2004-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
1TI8
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BU of 1ti8 by Molmil
H7 Haemagglutinin
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ...
著者Russell, R.J, Gamblin, S.J, Haire, L.F, Stevens, D.J, Xaio, B, Ha, Y, Skehel, J.J.
登録日2004-06-02
公開日2005-06-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.
Virology, 325, 2004
7A9D
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BU of 7a9d by Molmil
Crystal structure of H12 Haemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Xiong, X, Walker, P, Zhang, J, Gamblin, S, Skehel, J.J.
登録日2020-09-01
公開日2020-12-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hemagglutinin Structure and Activities.
Cold Spring Harb Perspect Med, 11, 2021

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