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PDB: 27 results

4XIR
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BU of 4xir by Molmil
Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors
Descriptor: (6S)-2-chloro-8,11,11-trimethyl-9-oxo-6-propyl-6,7,9,10,11,12-hexahydroindolo[2,1-d][1,5]benzoxazepine-3-carboxamide, GLYCEROL, Heat shock protein HSP 90-alpha
Authors:Neubert, T, Zuccola, H.J.
Deposit date:2015-01-07
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
4NH8
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BU of 4nh8 by Molmil
Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
Descriptor: 2-fluoro-6-[(3S)-tetrahydrofuran-3-ylamino]-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha
Authors:Ernst, J.T, Zuccola, H.J.
Deposit date:2013-11-04
Release date:2014-01-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Correlation between chemotype-dependent binding conformations of HSP90 alpha / beta and isoform selectivity-Implications for the structure-based design of HSP90 alpha / beta selective inhibitors for treating neurodegenerative diseases.
Bioorg.Med.Chem.Lett., 24, 2014
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數據於2024-07-17公開中

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