PDB クエリの検索結果 - 日本蛋白質構造データバンク

PDB: 27 件

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases
分子名称:	N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-2-methyl-N-(2,2,2-trifluoroethyl)-D-alaninamide, Tyrosine-protein kinase JAK2
著者	Ledeboer, M.W, Zuccola, H.J.
登録日	2015-03-17
公開日	2015-08-12
最終更新日	2016-07-20
実験手法	X-RAY DIFFRACTION (2.04 Å)
主引用文献	Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015

Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
分子名称:	2-fluoro-6-[(3S)-tetrahydrofuran-3-ylamino]-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha
著者	Ernst, J.T, Zuccola, H.J.
登録日	2013-11-04
公開日	2014-01-15
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Correlation between chemotype-dependent binding conformations of HSP90 alpha / beta and isoform selectivity-Implications for the structure-based design of HSP90 alpha / beta selective inhibitors for treating neurodegenerative diseases. Bioorg.Med.Chem.Lett., 24, 2014