4RLI
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![BU of 4rli by Molmil](/molmil-images/mine/4rli) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 | Descriptor: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | Authors: | Zhu, L, Ren, X, Zhu, J, Li, H. | Deposit date: | 2014-10-17 | Release date: | 2015-11-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 TO BE PUBLISHED
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4RK8
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![BU of 4rk8 by Molmil](/molmil-images/mine/4rk8) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356 | Descriptor: | 5-fluoro-2-{[(5Z)-5-(naphthalen-1-ylmethylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Ren, X, Zhu, J, Li, H. | Deposit date: | 2014-10-12 | Release date: | 2015-11-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A356 TO BE PUBLISHED
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3K1Q
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![BU of 3k1q by Molmil](/molmil-images/mine/3k1q) | Backbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics | Descriptor: | Core protein VP6, Outer capsid VP5, Outer capsid VP7, ... | Authors: | Cheng, L.P, Zhu, J, Hiu, W.H, Zhang, X.K, Honig, B, Fang, Q, Zhou, Z.H. | Deposit date: | 2009-09-28 | Release date: | 2010-03-23 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Backbone Model of an Aquareovirus Virion by Cryo-Electron Microscopy and Bioinformatics J.Mol.Biol., 397, 2010
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6IF2
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![BU of 6if2 by Molmil](/molmil-images/mine/6if2) | Complex structure of Rab35 and its effector RUSC2 | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Iporin, MAGNESIUM ION, ... | Authors: | Lin, L, Zhu, J, Zhang, R. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. Structure, 27, 2019
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6IF3
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![BU of 6if3 by Molmil](/molmil-images/mine/6if3) | Complex structure of Rab35 and its effector ACAP2 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Lin, L, Zhu, J, Zhang, R. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase. Structure, 27, 2019
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4JGD
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![BU of 4jgd by Molmil](/molmil-images/mine/4jgd) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016 | Descriptor: | 1-[4-methyl-2-(naphthalen-2-ylamino)-1,3-thiazol-5-yl]ethanone, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-01 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A016 TO BE PUBLISHED
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5XZR
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![BU of 5xzr by Molmil](/molmil-images/mine/5xzr) | The atomic structure of SHP2 E76A mutant in complex with allosteric inhibitor 9b | Descriptor: | 4-(3-phenylphenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3-thiazol-2-amine, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Li, D, Xie, J, Zhu, J, Liu, C. | Deposit date: | 2017-07-13 | Release date: | 2017-12-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment. J. Med. Chem., 60, 2017
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4JTS
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![BU of 4jts by Molmil](/molmil-images/mine/4jts) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072 | Descriptor: | 4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 To be Published
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6JIQ
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![BU of 6jiq by Molmil](/molmil-images/mine/6jiq) | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*T)-3'), SP_0782 | Authors: | Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2019-02-22 | Release date: | 2019-11-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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6JIP
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![BU of 6jip by Molmil](/molmil-images/mine/6jip) | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*T)-3'), PENTAETHYLENE GLYCOL, SP_0782 | Authors: | Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2019-02-22 | Release date: | 2019-11-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.659 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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4JTU
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![BU of 4jtu by Molmil](/molmil-images/mine/4jtu) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with brequinar analogue | Descriptor: | 6-bromo-2-{4-[(2R)-butan-2-yl]phenyl}-3-methylquinoline-4-carboxylic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Zhu, J, Ren, X, Li, H. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 To be Published
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4JS3
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![BU of 4js3 by Molmil](/molmil-images/mine/4js3) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 | Descriptor: | 2-chloro-4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETIC ACID, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Zhu, J, Ren, X. | Deposit date: | 2013-03-22 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 TO BE PUBLISHED
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4JTT
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![BU of 4jtt by Molmil](/molmil-images/mine/4jtt) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 066 | Descriptor: | 2,4-dimethyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Zhu, J, Ren, X. | Deposit date: | 2013-03-24 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057 TO BE PUBLISHED
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6IYN
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![BU of 6iyn by Molmil](/molmil-images/mine/6iyn) | Solution structure of camelid nanobody Nb26 against aflatoxin B1 | Descriptor: | Nb26 | Authors: | Nie, Y, He, T, Zhu, J, Li, S.L, Hu, R, Yang, Y.H. | Deposit date: | 2018-12-17 | Release date: | 2019-01-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Chemical shift assignments of a camelid nanobody against aflatoxin B1. Biomol NMR Assign, 13, 2019
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3KO1
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![BU of 3ko1 by Molmil](/molmil-images/mine/3ko1) | Cystal structure of thermosome from Acidianus tengchongensis strain S5 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperonin | Authors: | Huo, Y, Zhang, K, Hu, Z, Wang, L, Zhai, Y, Zhou, Q, Lander, G, He, Y, Zhu, J, Xu, W, Dong, Z, Sun, F. | Deposit date: | 2009-11-12 | Release date: | 2010-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Crystal structure of group II chaperonin in the open state. Structure, 18, 2010
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4LS1
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![BU of 4ls1 by Molmil](/molmil-images/mine/4ls1) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312 | Descriptor: | 2-[(E)-{2-[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Ren, X, Zhu, J. | Deposit date: | 2013-07-21 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A312 To be Published
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5GNV
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![BU of 5gnv by Molmil](/molmil-images/mine/5gnv) | Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain | Descriptor: | Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION | Authors: | Shang, Y, Xia, Y, Zhu, R, Zhu, J. | Deposit date: | 2016-07-25 | Release date: | 2017-08-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain Biochem. J., 474, 2017
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4LS2
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![BU of 4ls2 by Molmil](/molmil-images/mine/4ls2) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313 | Descriptor: | 2-[(E)-{2-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]hydrazinylidene}methyl]benzoic acid, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | Authors: | Zhu, L, Li, H, Ren, X, Zhu, J. | Deposit date: | 2013-07-21 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A313 To be Published
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4LS0
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![BU of 4ls0 by Molmil](/molmil-images/mine/4ls0) | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033 | Descriptor: | 2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzaldehyde, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Zhu, L, Li, H, Ren, X, Zhu, J. | Deposit date: | 2013-07-21 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033 To be Published
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1P4A
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![BU of 1p4a by Molmil](/molmil-images/mine/1p4a) | Crystal Structure of the PurR complexed with cPRPP | Descriptor: | 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE, Pur operon repressor | Authors: | Bera, A.K, Zhu, J, Zalkin, H, Smith, J.L. | Deposit date: | 2003-04-22 | Release date: | 2003-12-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Functional dissection of the Bacillus subtilis pur operator site. J.Bacteriol., 185, 2003
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4G5S
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![BU of 4g5s by Molmil](/molmil-images/mine/4g5s) | Structure of LGN GL3/Galphai3 complex | Descriptor: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | Deposit date: | 2012-07-18 | Release date: | 2012-09-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins To be Published
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5ZKL
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![BU of 5zkl by Molmil](/molmil-images/mine/5zkl) | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT12 | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), SP_0782 | Authors: | Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2018-03-24 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.951 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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5ZKM
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![BU of 5zkm by Molmil](/molmil-images/mine/5zkm) | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC | Descriptor: | DNA (5'-D(P*TP*CP*TP*TP*CP*C)-3'), SP_0782 | Authors: | Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | Deposit date: | 2018-03-24 | Release date: | 2019-03-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins. Nucleic Acids Res., 48, 2020
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8G57
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![BU of 8g57 by Molmil](/molmil-images/mine/8g57) | Structure of nucleosome-bound Sirtuin 6 deacetylase | Descriptor: | DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ... | Authors: | Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P. | Deposit date: | 2023-02-11 | Release date: | 2023-04-26 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Cryo-EM structure of the human Sirtuin 6-nucleosome complex. Sci Adv, 9, 2023
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8GYD
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![BU of 8gyd by Molmil](/molmil-images/mine/8gyd) | Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16 | Descriptor: | (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme | Authors: | Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X. | Deposit date: | 2022-09-22 | Release date: | 2023-08-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library. J.Med.Chem., 66, 2023
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